News Archive - 2013

News Archive - 2013

Getting to grips with migraine

Getting to grips with migraine

Researchers identify some of the biological roots of migraine from large-scale genome study

In the largest study of migraines, researchers have found five genetic regions that for the first time have been linked to the onset of migraine. This study opens new doors to understanding the cause and biological triggers that underlie migraine attacks.

Sequencing the MERS coronavirus outbreak in Saudi Arabia

Sequencing the MERS coronavirus outbreak in Saudi Arabia

Genetic tools and clinical techniques combine to characterise novel virus

Using deep sequencing technologies, researchers from the Kingdom of Saudi Arabia, US, Canada and the UK have shown that the novel Middle East Respiratory Syndrome (MERS) coronavirus can spread between people in healthcare settings.

Cartilage gene linked to bone cancers

Cartilage gene linked to bone cancers

Changes to cartilage linked to bone cancer offers a possible new diagnostic approach

For the first time, researchers from The Wellcome Trust Sanger Institute, the Royal National Orthopaedic Hospital and UCL Cancer Institute, have linked a gene central to the production of cartilage, COL2A1, to the development of a common type of bone cancer. Their discovery may act as an important way to diagnose this type of cancer in the future, improving patient care.

Professor Mike Stratton Knighted in the Birthday Honours list

Professor Mike Stratton Knighted in the Birthday Honours list

Recognition of research career to understand cancer

Professor Stratton has led international efforts to understand the genetic changes that cause cancer. In his early work he discovered BRCA2, one of the two major breast cancer susceptibility genes. Analysis of BRCA2 has been used to help hundreds of thousands of women around the world make informed decisions in managing their inherited risk of breast cancer.

Alliance will build data-sharing future

Alliance will build data-sharing future

World's health researchers join together to share and use 'big data'

More than 60 leading health care, research and disease advocacy organisations from across the world are joining together to form an international alliance dedicated to enabling secure sharing of genomic and clinical data.

Malaria's severity reset by mosquito

Malaria's severity reset by mosquito

The way malaria is transmitted controls how strongly the host's immune system reacts

For the first time, researchers have proven that the way in which malaria is transmitted to the host affects how severe the resulting infection will be.

Vaccine reduces pneumococcal disease but not bacterial population

Vaccine reduces pneumococcal disease but not bacterial population

Pre-existing bacterial strains fill the gaps made by the pneumococcal vaccine, but cause less disease

For the first time, researchers have tracked changes in an entire bacterial population following the introduction of a vaccine. They discovered that incidence of disease substantially reduced but the bacterium population has, unexpectedly, remained largely unchanged.

Fingerprinting malaria parasite drug resistance

Fingerprinting malaria parasite drug resistance

New genome sequencing technologies provide insight into emerging artemisinin resistance and a novel way to track this public health threat

Researchers have discovered multiple strains of the malaria-causing parasite Plasmodium falciparum that appear to be rapidly expanding throughout the local parasite population in Western Cambodia, a known hotspot for drug resistance. These strains have emerged recently and are all artemisinin-resistant.

Two cultures: Artists and scientists inspire each other

Two cultures: Artists and scientists inspire each other

Katie Paterson presents her work as part of the Wellcome Collection's Art in Global Health project

'Fossil Necklace', is made of 170 specially carved beads, with each bead representing a moment in time: threaded together they chart the evolution of life on earth. The oldest fossil is more than 3.5 billion years old.

Science and games - inspiring one another

Science and games - inspiring one another

Sanger Institute researchers work with teams to develop games based around genetics and genomics

Four Wellcome Trust Sanger Institute researchers have crossed into unknown territory to share their knowledge of genetics and genomics with the world of computer game development and design. Each of the researchers passed on their scientific wisdom and mentored a team in this year's Make Something Unreal Live contest, the UK and European student game development competition run by Epic Games, Inc.

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