COVID-19 Genomics Initiative at the Wellcome Sanger Institute
We are developing real-time genomic monitoring of the SARS-CoV-2 virus in the UK to aid public health response, and monitor genetic mutations which could allow the coronavirus to escape vaccines
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COVID-19 Surveillance Tool
This website shows how SARS-CoV-2 lineages have changed in frequency over time across England
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COVID-19 surveillance (as of 19 July 2021)
coronavirus genomes sequenced by the Sanger Institute
coronavirus genomes sequenced by the COVID-19 Genomics UK (COG-UK) consortium
Sanger staff have contributed to the 7-days-per-week operation
COVID-19 Surveillance delivery team
A roll call of the 300+ scientists, administrators and volunteers who are woking together to make Sanger's large-scale, high-throughput COVID-19 sequencing work happen
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COVID-19 Genomics UK (COG-UK) Protocols
The Institute is contributing a range of protocols on all aspects of large-scale, nation-wide virus sample and metadata collection, preparation, sequencing, analysis and data visualisation to the work of COG-UK
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Sanger Seminar: Comprehensive genomic surveillance of SARS-CoV-2 in the UK
Seminar: Exploring how the the Sanger Institute sequences SARS-CoV-2 genomes, and how this data is used by the COVID-19 Genomics UK (COG-UK) Consortium for surveillance and new variant identification; including the B.1.1.7 variant.
Q&A session with Dr Jeff Barrett, Director the Wellcome Sanger Institute COVID-19 Genomics Initiative.
Human Cell Atlas COVID-19 research
Through our collaborations within the Human Cell Atlas initiative, a number of our research teams are exploring how the SARS-CoV-2 virus interacts with the cells in the body to gain access and cause symptoms.
To find out more about this work, please visit: https://www.humancellatlas.org/covid-19/
Latest COVID-19 News and Blogs
29 Jun 2021
Covid Connections – Variant or Villain
The second COVID connections talk brought together experts from COG-UK to discuss SARS-CoV-2 variants.
27 May 2021
Genomics in a pandemic – Shedding light on the invisible
Experts from the COVID-19 Genomics UK Consortium discuss sequencing SARS-CoV-2, variants, and viral fitness landscapes.
18 May 2021
Car manufacturing, cellular biology and COVID
Rachel Nelson, head of the Cellular Generation and Phenotyping (CGaP) facility, reflects on managing science at scale, including the lessons ...
30 Apr 2021
Championing Team Science
Professor Muzlifah Haniffa shares her thoughts achieving large-scale science.
29 Mar 2021
Fighting Pathogens with Data and Partnerships
"Data analysis in genomics means that you can work in something that is meaningful."
25 Mar 2021
Salivary gland cells revealed as sites of COVID-19 infection
Human Cell Atlas findings point to role for saliva in SARS-CoV-2 transmission
17 Mar 2021
SARS-CoV-2 infects cells via specific viral entry factors that are more abundant in elderly, men and smokers
These findings offer a molecular explanation for the reported differences in disease severity for COVID-19 patients depending on age, gender and ...
11 Mar 2021
Genomic surveillance – the world’s binoculars focused on infectious diseases
Monitoring the microorganisms that cause COVID-19, malaria, cholera and a whole range of other diseases enables researchers to track outbreaks, ...
3 Mar 2021
Genomics study identifies routes of transmission of coronavirus in care homes
Genome sequencing was combined with detailed epidemiological information to examine the impact of COVID-19 on care homes and to discover how ...
12 Feb 2021
New COVID-19 saliva testing strategy could translate into easy-to-use home device
The new testing approach would be easier to collect and simpler to process in the laboratory than the current nasal-swab process.
5 Feb 2021
Sequencing COVID: our latest stats
As the sequencing hub of COG-UK, the Sanger Institute is sequencing the genomes of coronavirus samples from across the country. ...
25 Jan 2021
Looking Down a Microscope and Seeing Discoveries Happen
Andy Russell is a PhD Student in the Voet, Lawniczak, and Billker groups at the Sanger Institute, studying cancer and ...
21 Dec 2020
20 Things We Learned in 2020
This has been a year that none of us will forget in a hurry. The Institute is immensely proud of ...
19 Nov 2020
COG-UK computing effort wins collaboration award for COVID-19 work
HPCwire award recognises consortium's sequencing of tens of thousands of viral genomes
16 Nov 2020
Wellcome Sanger Institute and COG-UK receive £12.2M UK Government investment for COVID-19 real-time genomic surveillance system
Institute researchers will support the COVID-19 Genomics UK consortium's work by providing high-throughput virus genome sequencing, creating surveillance software to ...
22 Oct 2020
Sequencing COVID-19 at the Sanger Institute
This photo essay goes behind the scenes of the effort to sequence the genome of the COVID-19 virus at the ...
19 Aug 2020
The race to sequence SARS-CoV-2
The Sanger Institute is built for high-throughput science – but the project to sequence coronavirus demanded more samples were handled more ...
27 Jul 2020
Impact of The Technician Commitment
Kelly Vere, Programme Director of the Technician Commitment, explores the progress of the scheme across the UK.
16 Jul 2020
From bacterial behaviours to COVID-19
Sushmita Sridhar has paused her work on a gastroenteritis-causing bacterium to help diagnose the virus that causes COVID-19.
13 Jul 2020
Explore COVID-19 science in action with new Human Cell Atlas animation
Mapping COVID-19: How the Human Cell Atlas enhances our understanding of the disease
1 Jun 2020
From cancer, stem cells and organoids to COVID-19
Sanger scientists speak about their new roles in sequencing SARS-CoV-2 genomes.
22 May 2020
Analysis of COVID-19 Genomes reveals large numbers of introductions to the UK in March
The data reports, published by the COVID-19 Genomics UK Consortium (COG-UK), show the value in mapping COVID-19 lineages across the UK ...