Catch up on our previous talks

Comprehensive genomic surveillance of SARS-CoV-2 in the UK

Dr Jeff Barrett is Director the Wellcome Sanger Institute COVID-19 Genomics Initiative.

Hear how the Sanger Institute has sequenced more than 100,000 SARS-CoV-2 genomes, and how the COVID-19 Genomics UK (COG-UK) Consortium is using the data for surveillance, including the discovery and spread of the B.1.1.7 variant.

Dissecting the function of genetic variants associated with immune diseases

Dr Gosia Trynka is Group Leader at the Wellcome Sanger Institute and Experimental Science Director of Open Targets.

In her talk, Gosia describes how she uses genomics to identify cellular pathways and molecular targets that have been affected in immune diseases to develop new treatments and diagnostics.

Q&A with
Dr Gosia Trynka

The Q&A session with Dr Gosia Trynka, Group Leader in the Human Genetics Programme, at the Wellcome Sanger Institute and Experimental Science Director at Open Targets was hosted by the Sanger Institute’s:

• Dr Mathew Garnett, Group Leader (from the Cancer, Ageing and Somatic Mutation research programme)
• Dr Roser Vento-Tormo, Group Leader (from the Cellular Genetics research programme)
• Dr Julia Wilson, Associate Director (from the Director’s Office)

Charting the evolutionary journey towards malaria elimination

Professor Dominic Kwiatkowski is Head of the Parasites and Microbes research programme at the Sanger Institute.

In his talk, Dominic describes how he uses genomics to probe the ongoing evolutionary arms race between parasites, mosquitoes and human populations that are afflicted by malaria, and how this knowledge can be translated into new strategies for combatting drug and insecticide resistance.

Q&A with
Professor Dominic Kwiatkowski

The Q&A session with Professor Dominic Kwiatkowski, who leads the Parasites and Microbes research Programme, was hosted by the Sanger Institute’s:

• Dr Mathew Garnett, Group Leader (from the Cancer, Ageing and Somatic Mutation research programme)
• Dr Julia Wilson, Associate Director (from the Director’s Office)

Busy ’bout the tree of life: What telomere-to-telomere genome sequences tell us about global biodiversity

Professor Mark Blaxter leads the Tree of Life Programme which has as an overarching goal the sequencing to high quality of all species on Earth.

Discover how he and his colleagues are using genomics to:

• understand the deep roots of biodiversity,
• delve into the unique biology of threatened organisms and
• provide tools for conservation and mitigation of climate change and other threats.

Q&A with
Professor Mark Blaxter

The Q&A session with Professor Mark Blaxter, who leads the Tree of Life Programme, was hosted by the Sanger Institute’s:

• Dr Mathew Garnett, Group Leader (from the Cancer, Ageing and Somatic Mutation research programme)
• Dr Roser Vento-Tormo, Group Leader (from the Cellular Genetics research programme)

Stratifying sepsis patients through transcriptomic profiling

Dr Emma Davenport, Group Leader in the Human Genetics Programme at the Sanger Institute discussed somatic mutations, and how her research team is using gene expression data to understand how individuals respond to sepsis, a life-threatening condition caused by the dysregulated host response to infection.

Q&A with Dr Emma Davenport

The Q&A session with Dr Emma Davenport, Group Leader in the Human Genetics Programme, was hosted by the Sanger Institute’s:

• Dr Mathew Garnett, Group Leader (from the Cancer, Ageing and Somatic Mutation research programme)
• Dr Roser Vento-Tormo, Group Leader (from the Cellular Genetics research programme)
• Dr Julia Wilson, Associate Director (from the Director’s Office)

Somatic mutations in normal tissues

Dr Peter Campbell, Head of Cancer, Ageing and Somatic Mutation programme at the Sanger Institute discussed somatic mutations, and how researchers are characterising the landscape of mutations in cells to provide insights into normal tissue development and maintenance, cancer evolution, diseases other than cancer, and ageing.

Q&A with Dr Peter Campbell

The Q&A session with Dr Peter Campbell, Head of Cancer, Ageing and Somatic Mutation programme, was hosted by the Sanger Institute’s:

• Dr Mathew Garnett, Group Leader (from the Cancer, Ageing and Somatic Mutation research programme)
• Dr Roser Vento-Tormo, Group Leader (from the Cellular Genetics research programme)
• Dr Julia Wilson, Associate Director (from the Director’s Office)

Human Cell Atlas: Mapping the body one cell at a time

The Human Cell Atlas is an ambitious global initiative aiming to create a comprehensive reference map of all human cells—the fundamental units of life—as a basis understanding human health and diagnosing, monitoring, and treating disease.

In this talk Dr Sarah Teichmann explains how the Human Cell Atlas is providing unprecedented understanding of human cells and tissue architecture in health and disease including reproductive biology, auto-immune disease and Covid-19 infection.

Q&A with Dr Sarah Teichmann

The Q&A session with Dr Sarah Teichmann, Head of the Cellular Genetics research programme, was hosted by the Sanger Institute’s:

• Dr Mathew Garnett, Group Leader (from the Cancer, Ageing and Somatic Mutation research programme)
• Dr Roser Vento-Tormo, Group Leader (from the Cellular Genetics research programme)
• Dr Julia Wilson, Associate Director (from the Director’s Office)