Wellcome Sanger Institute researchers and collaborators found that patients with acute myeloid leukaemia (AML) had genetic changes in their blood years before they suddenly developed the disease. The study published in Nature shows that further research could allow earlier detection and monitoring of people at risk of AML in the future.

For the first time, the transmission of cholera has been tracked at the household level across Dhaka, Bangladesh, a city with a ‘hyper-endemic’ level of the disease. Researchers from the Wellcome Sanger Institute and their collaborators found that nearly 80 per cent of the cholera transmission in Dhaka occurred between people who shared a household. The results of the large-scale genomic study could be used by public health officials to improve cholera control strategies.