Explore our programmes
Cancer, Ageing and Somatic mutation
Provides data aggregation and informatics innovation, develops high-throughput cellular models of cancer for genome-wide functional screens and drug testing, and explores the role somatic mutation plays in clonal evolution, ageing and development. Find out more
Uses single-cell approaches and “cell atlas” technologies to understand human genetics at the cellular level. Combines cutting-edge techniques in wet and dry lab to further understanding of human health, development and disease. Find out more
Drives understanding of genetic causes and biological mechanisms of disease susceptibility and progression, focuses on developmental disorders and diseases of the blood and immune system. Integrates population-scale genetics, longitudinal clinical data, and large-scale genetic perturbation studies in cellular model systems. Aims to transform the clinical utility of human genetic variation. Find out more
Parasites and Microbes
We are using genomics to get at important problems in infectious disease, with a strong desire to translate this into tools for disease control and elimination, but we are also at the forefront of basic research into microbial ecology, evolutionary genetics and the biology of parasitism. Find out more
Explore our science
Our research is built upon our Faculty and Associate Faculty research leaders. Each develops his or her own hypothesis-driven research, seeking answers to important biomedical questions. Faculty and Associate Faculty members lead their own groups of postdoctoral fellows, PhD students and support staff.
Find out more
Our ability to conduct large-scale, high-throughput genomic studies enables our researchers to play leading roles in national and international projects: spanning cancer, infectious disease, human epidemiology and developmental disorders.
Find out more
All our software tools are made available to the research community and comply with our open-access policy, recognising that community improvement is essential to maximising efficiencies in software development.
Find out more
Sanger Seminar Series
We are hosting a series of monthly freely available and open virtual seminars, showcasing how our researchers are tackling some of the greatest challenges in human health and disease. From using genomic approaches to map all cell types in the human body, understand how cancer develops, and track the evolution and spread of global diseases, our senior scientists and faculty will present the latest developments in their field.
30 Jul 2020
New drug targets for lethal brain cancer discovered
Researchers engineered a new mouse model for studying glioblastoma, the most aggressive type of brain cancer
21 Jul 2020
Chronic inflammation alters the evolution of cells in the colon, study finds
Researchers have compared diseased colon with healthy tissue to better understand how inflammatory bowel disease (IBD) is linked to an increased ...