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On average, healthy cells in the oesophagus carry at least several hundred mutations per cell in people in their twenties, rising to over 2,000 mutations per cell later in life

Wellcome Sanger Institute, Genome Research Ltd

Mutant cells colonise our tissues over our lifetime

Scientists may need to rethink the role of some cancer genes in the light of sequencing normal tissues

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Apply to the Sanger Institute's PhD programmes
One of our core aims is to train the next generation of world class genome scientists and clinicians
The application closing date for the 4-year PhD programme is: Monday 3rd December 2018 (09:00 GMT).The application closing date for the clinical PhD programme is: Thursday 15th November 2018 (noon GMT) ...more

Recent News

Milestone reached in major developmental disorders project

Eight years after launch, the Deciphering Developmental Disorders project has identified 49 completely new disorders and provided diagnoses to 4,500 children with rare diseases

Genetics allows personalised disease predictions for chronic blood cancers

The approach could help doctors identify which patients may benefit from specific treatments or clinical trials

25 UK species' genomes sequenced for first time

The high-quality genomes will be made freely available to scientists to use in their research