News Archive

News Archive

Kidney cancer's developmental source revealed

Section of human kidney cortex - Researchers have discovered that children’s Wilms’ cancer cells have the same characteristics as a specific normal developing kidney cell, indicating that these kidney cells failed to develop properly in the womb

Kidney cancer's developmental source revealed

Study reveals that kidney cancers may arise from cells that haven't fully developed, offering a new target for treatment

Using single-cell RNA sequencing, the researchers discovered that children’s Wilms’ cancer cells have the same characteristics as a specific normal developing kidney cell, indicating that these kidney cells failed to develop properly in the womb.

Human Cell Atlas gets a boost with first funding from Wellcome

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Human Cell Atlas gets a boost with first funding from Wellcome

Injection of £7 million will help to create a cellular 'Google map' of the human body, which could revolutionise health and disease

The funding announced today (9 August) is the first major financial commitment in the UK to power the collection, sequencing, and analysis of cells. It will build on the UK’s long history of excellence in genomics and biomedical research, aided by strong links between research groups, tissue biobanks, and hospitals.

Explore nature's genetic secrets in new exhibition

Curious Nature exhibition at the Wellcome Genome Campus. Image Credit: Alex Cagan, Genome Research Limited

Explore nature's genetic secrets in new exhibition

Curious Nature exhibition explores the Wellcome Sanger Institute’s 25th anniversary project to sequence the genomes of 25 UK species for the first time.

Discover how genome sequencing is helping us uncover much more about the world around us in Wellcome Genome Campus’ new family-friendly exhibition, Curious Nature. The exhibition is part of Open Saturdays at the Campus, which are free to attend but booking is required.

Gene study pinpoints superbug link between people and animals

Gene study pinpoints superbug link between people and animals

Gene study pinpoints superbug link between people and animals

The research could help with designing more effective ways to prevent bacterial transfer in farms and better antibiotic practices

The findings, published today (23 July) in Nature Ecology & Evolution, reveal fresh insights into how new disease-causing strains of the bacteria – called Staphylococcus aureus – emerge.

Omer Bayraktar to lead new research group in the Cellular Genetics Programme

Mouse brain: Omer Bayraktar will be leading a new Faculty research group at the Wellcome Sanger Institute to study single cells in the human and mouse cortex

Omer Bayraktar to lead new research group in the Cellular Genetics Programme

The Faculty appointment, starting in August 2018, will develop high-throughput pipelines to map human tissues one cell at a time

The Wellcome Sanger Institute is pleased to announce that Omer Bayraktar will be joining its Cellular Genetics Faculty in August 2018 to create a map of the individual cells and networks in the cortex of the human brain. Omer’s work will help to lay the foundations needed to understand how this complex region of the brain develops and functions.

Genome damage from CRISPR/Cas9 gene editing higher than thought

Genome damage from CRISPR/Cas9 gene editing higher than thought

Genome damage from CRISPR/Cas9 gene editing higher than thought

Caution required for using CRISPR/Cas9 in potential gene therapies

The study in Nature Biotechnology revealed that standard DNA tests miss finding this genetic damage. This has safety implications for future gene therapies using CRISPR/Cas9, because the unexpected damage might lead to dangerous changes in some cells. The authors caution that specific testing may be required for potential gene therapies.

Roots of leukaemia reveal possibility of predicting people at risk

Acute Myeloid Leukaemia (AML)

Roots of leukaemia reveal possibility of predicting people at risk

Mutations in blood identify individuals at high risk of developing leukaemia

Wellcome Sanger Institute researchers and collaborators found that patients with acute myeloid leukaemia (AML) had genetic changes in their blood years before they suddenly developed the disease. The study published in Nature shows that further research could allow earlier detection and monitoring of people at risk of AML in the future.

Cholera spread tracked at household level

For the first time, the transmission of cholera has been tracked at the household level across Dhaka, Bangladesh, a city with a ‘hyper-endemic’ level of the disease.

Cholera spread tracked at household level

The results could be used by public health officials to improve cholera control strategies

For the first time, the transmission of cholera has been tracked at the household level across Dhaka, Bangladesh, a city with a ‘hyper-endemic’ level of the disease. Researchers from the Wellcome Sanger Institute and their collaborators found that nearly 80 per cent of the cholera transmission in Dhaka occurred between people who shared a household. The results of the large-scale genomic study could be used by public health officials to improve cholera control strategies.

Wellcome Sanger Institute calls for the free movement of scientists across European borders following Brexit

Wellcome Sanger Institute calls for the free movement of scientists across European borders following Brexit

Wellcome Sanger Institute calls for the free movement of scientists across European borders following Brexit

The Institute has provided evidence for the UK Government Science and Technology Committee’s inquiry into an immigration system that works for science and innovation

In response to the UK Parliament Science and Technology Committee’s inquiry, the Sanger Institute has made a number of recommendations: that the current immigration system is not fit for purpose and therefore it should not be transposed onto EEA nationals, once the UK leaves the EU and that Students from EEA countries who have completed undergraduate qualifications in the UK should be given time to remain in the UK to allow them to look for work.

Genomics offers new treatment options for infants with range of soft tissue tumours

Genomics offers new treatment options for infants with range of soft tissue tumours

Genomics offers new treatment options for infants with range of soft tissue tumours

Scientists uncover the genetic changes causing a group of related infant cancers

The genetic causes of a group of related infant cancers have been discovered by scientists at the Wellcome Sanger Institute, the University of Wuerzburg and their collaborators. Whole genome sequencing of tumours revealed mutations which are targetable by existing drugs used to treat lung cancer and melanoma.

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