News Archive

News Archive

Darwin Tree of Life sets down roots

Participants at the March 2019 Darwin Tree of Life planning meeting

Darwin Tree of Life sets down roots

Planning for the Darwin Tree of Life Project is underway. We welcome Professor Mark Blaxter, from the University of Edinburgh, who will join the Sanger Institute and work alongside a scientific working group to establish the Institute’s new research programme, Tree of Life

The Darwin Tree of Life Project is just one of several initiatives across the globe working towards the ultimate goal of sequencing all complex life on Earth, in a venture known as the Earth BioGenome Project. The Sanger Institute will serve as a hub for sequencing and assembling the genomes of species from the British Isles. It will collaborate with partners from a breadth of UK-wide institutions, museums and universities to identify and collect species, and then to annotate and share the genomes.

Commitment to collaborate on using genomics for pathogen surveillance across Europe

Leaders from the Wellcome Sanger Institute and the European Centre for Disease Prevention and Control have signed a framework collaboration agreement to help enable and improve the use of genomic technologies in monitoring dangerous bacteria in the Europe

Commitment to collaborate on using genomics for pathogen surveillance across Europe

Combining the strengths of the European Centre for Disease Prevention and Control, the Wellcome Sanger Institute and the Centre for Genomic Pathogen Surveillance will improve the monitoring and tracking of infectious disease across Europe

Leaders from the Wellcome Sanger Institute and the European Centre for Disease Prevention and Control have signed a framework collaboration agreement, agreeing to work in partnership to help enable and improve the use of genomic technologies in monitoring dangerous bacteria in the European Union and European Economic Area.

Champions of equality and diversity celebrated

Winners of the Wellcome Genome Campus 2019 Best Practice for Supporting Equality and Diversity in Science Awards

Champions of equality and diversity celebrated

The winners were nominated by staff working at the Wellcome Genome Campus for their actions to advance equality, diversity and inclusion, which has positively impacted colleagues' working lives

For International Women's Day today (8 March) the Wellcome Genome Campus is celebrating its staff who lead the way in supporting equality and diversity in science. The day is being marked with its annual award for Best Practice for Supporting Equality and Diversity in Science.

Major mutation pattern in cancer occurs in bursts

Major mutation pattern in cancer occurs in bursts

Major mutation pattern in cancer occurs in bursts

New resource could help understand origins of cancer

Researchers have created a huge resource for investigating the biological mechanisms that cause cancer. Scientists from the Wellcome Sanger Institute and their collaborators identified the patterns of DNA damage - mutational fingerprints that represent the origins of cancer - present in over a thousand human cancer cell lines. They revealed that a major mutation pattern found in human cancer, occurred in bursts in cancer cell lines. Understanding these mutational processes could help research towards cancer prevention and treatment.

Cambridge heart research boosted by £6 million British Heart Foundation Research Excellence Award

Cambridge heart research boosted by £6 million British Heart Foundation Research Excellence Award

Cambridge heart research boosted by £6 million British Heart Foundation Research Excellence Award

Funding will allow Sanger Institute researchers and collaborators to apply cutting-edge genomics to help develop new heart disease diagnostics and treatments

The British Heart Foundation (BHF) has announced it will double its funding into world-leading heart disease research at the University of Cambridge’s BHF Centre of Research Excellence. The charity has awarded Cambridge a £6 million Research Excellence Award, so that it can expand and accelerate its pioneering work at the centre over the next five years.

Roser Vento-Tormo leads single-cell research team at the Sanger Institute

Vento-Tormo Group (VenTo group)

Roser Vento-Tormo leads single-cell research team at the Sanger Institute

The new group will identify the cells involved in the human female reproductive system, how they work, organise and communicate with each other to understand infertility, pre-eclampsia, miscarriage, placental defects and cancer

The Wellcome Sanger Institute is delighted that Roser Vento-Tormo has become its latest member of Faculty in March 2018. Her research team will boost the work of the Cellular Genetics programme as it explores the cellular makeup of, and interactions between, the individual cells that make up a human body.

Improving global surveillance of antibiotic resistance

Improving global surveillance of antibiotic resistance

Improving global surveillance of antibiotic resistance

A WHO Technical Note has been published that will enable health authorities to make informed choices on the most appropriate molecular tests in order to achieve a clearer picture of antimicrobial resistance globally

The WHO Technical Note details how molecular diagnostic tests using DNA or proteins can give reliable data that can complement current methods. The Technical Note considers three different laboratory contexts, each with different levels of capacities for molecular AMR testing: those with no prior experience in molecular AMR surveillance; newly established national reference laboratories (NRLs); and fully established NRLs with experience in molecular AMR surveillance.

Establishing the molecular blueprint of early embryo development

Establishing the molecular blueprint of early embryo development

Establishing the molecular blueprint of early embryo development

By studying the genetic activity of 116,312 single cells from 6.5 to 8.5 days after fertilisation, researchers have determined the molecular blueprint for mouse embryonic development

A pioneering group of biologists, physicists and mathematical modellers in Cambridge have studied the genetic activity of over 100,000 embryonic cells to establish the molecular blueprint of mouse early embryo development. This new research provides fundamentally important information on how mammalian embryos develop during gastrulation, a key stage of development, and paves the way for new understanding of the earliest stages of life.

Cancer comparison across species highlights new drug target

Cancer comparison across species highlights new drug targets

Cancer comparison across species highlights new drug target

Scientists discover key genes for mucosal melanoma in humans, dogs and horses that help prioritise targets for new cancer therapies

The results, reported in Nature Communications, give insights into how cancer evolves across the tree of life and could guide the development of new therapies.

Almost 2,000 unknown bacteria discovered in the human gut

Almost 2,000 unknown bacteria discovered in the human gut

Almost 2,000 unknown bacteria discovered in the human gut

Researchers identify novel gut bacteria species and call for more data from beyond Europe and North America

Researchers at the Wellcome Sanger Institute and EMBL’s European Bioinformatics Institute have identified almost 2,000 bacterial species living in the human gut. These species are yet to be cultured in the lab. The team used a range of computational methods to analyse samples from individuals worldwide.

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