News Archive

News Archive

First seeds of kidney cancer sown in adolescence

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First seeds of kidney cancer sown in adolescence

Insights from this study present an opportunity to develop approaches for early detection and early intervention in kidney cancer

The earliest critical genetic changes that can lead to kidney cancer have been mapped by scientists. The first key genetic change occurs in childhood or adolescence, and the resulting cells follow a consistent path to progress into kidney cancer four or five decades later, scientists have found.

Single cell technology and organoids reveal every bowel tumour and bowel cancer cell have unique genetic fingerprints

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Single cell technology and organoids reveal every bowel tumour and bowel cancer cell have unique genetic fingerprints

Study could help researchers target cancer-specific processes for cancer prevention or to develop treatments

New research on bowel cancer has shown that every tumour is different, and that every cell within the tumour is genetically unique. In the first study of its kind, researchers used the latest single cell and organoid technologies to understand the mutational processes of the disease. This study could help researchers target cancer-specific processes for prevention or treatment.

20 year-old mystery of malaria vaccine target solved

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20 year-old mystery of malaria vaccine target solved

Discovery of human receptor for TRAP protein could help improve development of an effective malaria vaccine

A long-standing mystery of how the high-priority malaria vaccine target TRAP interacts with human host cells has been solved. Wellcome Sanger Institute scientists have discovered a receptor protein on the surface of human cells that the malarial TRAP protein interacts with as it navigates through the body. This could help improve the development of an effective malaria vaccine.

Whole genome sequencing will ‘transform the research landscape for a wide range of diseases’

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Whole genome sequencing will ‘transform the research landscape for a wide range of diseases’

UK Biobank enters exciting new phase of genetics research

UK Biobank announces today (6 April) a major initiative to sequence the full genomes of 50,000 UK Biobank volunteer participants. Funded by a £30M grant from the Medical Research Council (MRC), sequencing of the whole genome will be undertaken during 2018 and 2019 by the Wellcome Sanger Institute. With the ultimate goal to sequence all 500,000 UK Biobank participants, the investment will help establish the world’s most detailed whole genome database – and further accelerate research into a wide range of diseases that cause disability and premature death in mid to later life.

Malaria Cell Atlas launched: Parasite development mapped in unprecedented detail

Malaria Cell Atlas launched: Parasite development mapped in unprecedented detail

Malaria Cell Atlas launched: Parasite development mapped in unprecedented detail

The Malaria Cell Atlas will allow researchers to identify weak points in the parasite’s lifecycle for intervention with drugs

New single-cell technology has allowed scientists to study malaria parasites at the highest resolution to date. By investigating the genes in individual malaria parasites, scientists are beginning to understand the genetic processes each parasite undergoes as it moves through its complicated lifecycle. The results are the first step towards developing the Malaria Cell Atlas, a data resource will allow researchers to identify weak points in the parasite’s lifecycle for intervention with drugs.

New online course launched to help doctors and nurses better understand how genomics can battle bacterial diseases

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New online course launched to help doctors and nurses better understand how genomics can battle bacterial diseases

Free three week course on Bacterial Genomes: Disease Outbreaks and Antimicrobial Resistance starts on April 30th

Wellcome Genome Campus Advanced Courses and Scientific Conferences (ACSC) today (Tuesday 27 March) announces the launch of its first online course, in partnership with FutureLearn, the leading social learning platform. The free online course introduces the genomics of disease-causing bacteria, such as MRSA, E. coli and Chlamydia which infect millions of people every year, and is open to anyone for enrolment now, with the course starting on April 30th 2018.

NUCLEUS project welcomes new consortium member: Wellcome Genome Campus in Cambridge

NUCLEUS Project group meeting - part of Horizon 2020

NUCLEUS project welcomes new consortium member: Wellcome Genome Campus in Cambridge

The ambitious HORIZON 2020 NUCLEUS project has been further strengthened by the joining of the Wellcome Genome Campus in Cambridge, UK as the 25th member of the consortium

A principal contribution of the Wellcome Genome Campus will be to offer coordination and support for three Responsible Research and Innovation (RRI) test beds called ‘Embedded Nuclei’. Dr Ken Skeldon, Head of Wellcome Genome Campus Public Engagement, based within Connecting Science, will lead the mentorship of these three research institutions, two of which are in Germany with the other in China.

Sanger Institute opens up its life sciences leadership development courses

Management & Leadership Development Programmes. The Sanger Institute's Scientific Education & Excellence Development (SEED) scheme is designed for research and life sciences organisations looking to develop their leadership potential

Sanger Institute opens up its life sciences leadership development courses

Five bespoke courses tailored to the needs of leaders at all levels, from new supervisors to established managers, are being offered to the scientific community

Sanger’s Scientific Education and Excellence Development (SEED) Scheme offers five leadership development programmes to enable leaders across the life sciences industry to take their leadership skills to the next level. Through interactive training sessions, feedback and personality profiling, participants will have the opportunity to build meaningful networks, share best practice ideas and develop behaviours that will drive their own success and that of their teams.

First 'non-gene' mutations behind neurodevelopmental disorders discovered

First 'non-gene' mutations behind neurodevelopmental disorders found, as part of the Deciphering Developmental Disorders (DDD) project

First 'non-gene' mutations behind neurodevelopmental disorders discovered

The study is a positive step towards providing an explanation for children with undiagnosed neurodevelopmental disorders

In the largest study of its kind, genetic changes causing neurodevelopmental disorders have been discovered by scientists at the Wellcome Sanger Institute and their collaborators in the NHS Regional Genetics services. The study of almost 8,000 families, published in Nature, found for the first time that mutations outside of genes can cause rare developmental disorders of the central nervous system.

Switch discovered to convert blood vessels to blood stem cells during embryonic development

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Switch discovered to convert blood vessels to blood stem cells during embryonic development

Findings could aid research into creating new blood cells for transplants and understanding cancer metastasis

A switch has been discovered that instructs blood vessel cells to become blood stem cells during embryonic development in mice. Reported in eLife, the findings from researchers from the Wellcome Sanger Institute in Cambridge and the European Molecular Biology Laboratory in Rome could aid research into creating new blood cells for transplants and for understanding cancer metastasis.

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