Major mutation pattern in cancer occurs in bursts
Researchers have created a huge resource for investigating the biological mechanisms that cause cancer. Scientists from the Wellcome Sanger Institute and their collaborators identified the patterns of DNA damage - mutational fingerprints that represent the origins of cancer - present in over a thousand human cancer cell lines. They revealed that a major mutation pattern found in human cancer, occurred in bursts in cancer cell lines. Understanding these mutational processes could help research towards cancer prevention and treatment.