Contact the Press Office

Dr Samantha Wynne, Media Officer

Tel +44 (0)1223 492 368

Emily Mobley, Media Officer

Tel +44 (0)1223 496 851

Wellcome Sanger Institute,
CB10 1SA,

Mobile +44 (0) 7900 607793

  • Loose ends: almost one in five human genes still have unresolved coding status.

    Abascal F, Juan D, Jungreis I, Martinez L, Rigau M et al.

    Nucleic acids research 2018

  • Prediction of acute myeloid leukaemia risk in healthy individuals.

    Abelson S, Collord G, Ng SWK, Weissbrod O, Mendelson Cohen N et al.

    Nature 2018

  • Crumble: reference free lossy compression of sequence quality values.

    Bonfield JK, McCarthy SA and Durbin R

    Bioinformatics (Oxford, England) 2018

  • Fluoroquinolone resistance in Salmonella: insights by whole-genome sequencing.

    Cuypers WL, Jacobs J, Wong V, Klemm EJ, Deborggraeve S and Van Puyvelde S

    Microbial genomics 2018

  • A Requirement for Zic2 in the Regulation of Nodal Expression Underlies the Establishment of Left-Sided Identity.

    Dykes IM, Szumska D, Kuncheria L, Puliyadi R, Chen CM et al.

    Scientific reports 2018;8;1;10439

  • Detection and removal of barcode swapping in single-cell RNA-seq data.

    Griffiths JA, Richard AC, Bach K, Lun ATL and Marioni JC

    Nature communications 2018;9;1;2667

  • No unexpected CRISPR-Cas9 off-target activity revealed by trio sequencing of gene-edited mice.

    Iyer V, Boroviak K, Thomas M, Doe B, Riva L et al.

    PLoS genetics 2018;14;7;e1007503

  • BCL11B mutations in patients affected by a neurodevelopmental disorder with reduced type 2 innate lymphoid cells.

    Lessel D, Gehbauer C, Bramswig NC, Schluth-Bolard C, Venkataramanappa S et al.

    Brain : a journal of neurology 2018

  • Genome-wide CRISPR-KO Screen Uncovers mTORC1-Mediated Gsk3 Regulation in Naive Pluripotency Maintenance and Dissolution.

    Li M, Yu JSL, Tilgner K, Ong SH, Koike-Yusa H and Yusa K

    Cell reports 2018;24;2;489-502

  • The prehistoric peopling of Southeast Asia.

    McColl H, Racimo F, Vinner L, Demeter F, Gakuhari T et al.

    Science (New York, N.Y.) 2018;361;6397;88-92

  • ESBL-plasmid carriage in <i>E. coli</i> enhances in vitro bacterial competition fitness and serum resistance in some strains of pandemic sequence types without overall fitness cost.

    Ranjan A, Scholz J, Semmler T, Wieler LH, Ewers C et al.

    Gut pathogens 2018;10;24

  • Single-cell biology: resolving biological complexity, one cell at a time.

    Ranzoni AM and Cvejic A

    Development (Cambridge, England) 2018;145;13

  • Cold-induced epigenetic programming of the sperm enhances brown adipose tissue activity in the offspring.

    Sun W, Dong H, Becker AS, Dapito DH, Modica S et al.

    Nature medicine 2018