Babies' gut bacteria affected by delivery method, Baby Biome project shows
Salmonella responsible for bloodstream infections in central Africa resistant to nearly all drugs
The first extensively drug-resistant (XDR) strains of Salmonella Typhimurium, a pathogen which is responsible for millions of bloodstream infections per year in sub-Saharan Africa, have been identified in the Democratic Republic of Congo (DRC). Drug-resistance has increased in successive groups of S. Typhimurium over time. These new strains are resistant to all but one of the commonly available drugs in the DRC, with one sample showing reduced susceptibility to this final antibiotic.
500,000 whole human genomes will be a game-changer for research into human diseases
In a major advance for public health and for the UK’s global leadership in genomics, a £200m project involving the government, charity, researchers and four leading pharmaceutical companies, was announced today (11 September). The Whole Genome Sequencing (WGS) project will become a game-changing resource accessible to the global scientific community to understand, diagnose, treat and prevent life-changing diseases such as cancer and dementia.
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Single-cell landscape in mammary epithelium reveals bipotent-like cells associated with breast cancer risk and outcome.
Communications biology 2019;2;306
STXBP1-associated neurodevelopmental disorder: a comparative study of behavioural characteristics.
Journal of neurodevelopmental disorders 2019;11;1;17
Distinct Molecular Trajectories Converge to Induce Naive Pluripotency.
Cell stem cell 2019;25;3;388-406.e8
The origins and relatedness structure of mixed infections vary with local prevalence of P. falciparum malaria.