Research project
Genome assemblies for 25 species across the Notothenioid radiation
The Notothenioids are a group of Percomorph fish and constitute one of the best characterized marine radiations. Notothenioids consist of over ...
Visualising, analysing and browsing next generation sequence data
Examples and use cases for Artemis are shown below.
Open-access data portals
The Cellular Genetics Programme is committed to making cell atlasing data analysis and visualisation tools available to the scientific community
Open access tools
Computational tools developed by the research groups and scientific teams of the Cellular Genetics Programme
originally developed in Martin Hemberg's group
Cellular Genetics scRNA-seq analysis course
Combinatorial screen in a panel of mesothelioma cell lines
We have carried out a combinatorial screen in a panel of mesothelioma cell lines of 2,697 2-drug combinations and ...
Our plasmid collections can be browsed and ordered from our EXtracellular Plasmid RESource (EXPRESs) at Addgene.
The hematopoietic system provides a good model system to inform interpretation of association studies owing to simple phenotypes at the ...
As the impact of the human reference genome assembly on biomedical research has shown, the availability of a high quality ...
The use of genome-wide forward genetic screens to define the landscape of drug resistance drivers in cancer.
Cancer Ageing and Somatic Mutation research
In collaboration with the Andrea Bertotti lab at University of Turin we plan to sequence 500 human colorectal PDX models.
Whole genome and targeted gene screens in primary and recurrent anaplastic meningiomas.
We are using siKinome and genome-wide CRISPR/Cas9 lethality screens in colorectal cancer cell lines to identify novel vulnerabilities.
The genomics of rapid speciation in Lake Malawi cichlids
Genome sequences of cichlid fish for studies in speciation and evolutionary genomics
HAVANA team
The HAVANA team manually annotate the human, mouse, zebrafish and other vertebrate genomes.
PlasmoGEM provides the malaria research community with a variety of resources currently focusing on P.berghei , P falciparum and P. ...
What is synthetic genomics?
Scientists at the Sanger Institute are looking for new ways to study our DNA.
Miska Lab
This line of research pursues the identification of major molecular players involved in epigenetic inheritance in mammals. We are especially interested ...
The Vertebrate Genomes Project
The Vertebrate Genomes Project (VGP) at the Sanger Institute aims to provide reference quality assemblies for hundreds of fish, rodents ...
COVID-19 Surveillance Team
The SARS-CoV2 genome sequences produced by the Wellcome Sanger Institute are the result of a team effort by many people from ...
Wellcome Trust Strategic Award - The Homunculus in our Thymus: A Cellular Genomics Approach
We have been granted a strategic award from the Wellcome Trust 'The Homunculus in our Thymus: A Cellular Genomics Approach' that ...
This project aims at elucidating the function of piRNAs - small germline-specific non-coding RNAs - in different vertebrates.