HipSci brings together diverse constituents in genomics, proteomics, cell biology and clinical genetics to create a UK national iPS cell resource and use it to carry out cellular genetic studies. It aims to generate iPS cells from over 500 healthy individuals and 500 individuals with genetic disease. These cells will then be used to discover how genomic variation impacts on cellular phenotype and identify new disease mechanisms.
Using outbred genetic variation to understand basic biology
DNA sequence remains at the heart of molecular biology and bioinformatics. The Birney Associate Faculty Research Group at the Sanger ...
Cellular Generation and Phenotyping
The Cellular Generation and Phenotyping (CGaP) core facility provides central cell biology support to the Sanger Institute. CGaP takes a unique ...
Population and evolutionary genomics, novel computational genomics methods, and related mathematical and statistical models.