Wellcome Sanger Institute, Genome Research Limited

The Cancer Dependency Map integrates the work of multiple experimental and computational research project at the Sanger Institute with the shared aim of identifying dependencies in cancer cells which could be exploited to develop new therapies. This knowledge is foundational for our understanding of cancer biology and the development of precision cancer medicine.

About the Cancer Dependency Map

The consequences of alterations in the DNA of cancer cells and subsequent vulnerabilities are not fully understood. This project aims to assign a dependency to every cancer cell in a patient which could be exploited to develop new therapies.

Further details about the different laboratories and projects at the Sanger Institute contributing to the Cancer Dependency Map can be found at our Dependency Map website.


If you need help or have any queries, please contact us using the details below.

External partners and funders


The Broad Institute of MIT and Harvard

We are working closely with the Cancer Program at the Broad Institute to develop a high quality dependency map as a resource for the community.