Cancer Dependency Map
The Cancer Dependency Map integrates the work of multiple experimental and computational research project at the Sanger Institute with the shared aim of identifying dependencies in cancer cells which could be exploited to develop new therapies. This knowledge is foundational for our understanding of cancer biology and the development of precision cancer medicine.
About the Cancer Dependency Map
The consequences of alterations in the DNA of cancer cells and subsequent vulnerabilities are not fully understood. This project aims to assign a dependency to every cancer cell in a patient which could be exploited to develop new therapies.
Further details about the different laboratories and projects at the Sanger Institute contributing to the Cancer Dependency Map can be found at our Dependency Map website.
External partners and funders
Experimental Cancer Genetics
We are a team of cancer biologists, geneticists and computational biologists interested in understanding how cancers develop and the ways ...
Cancer Genome Project
Cancer Genetics & Genomics
Throughout life, the genome within cells of the human body is exposed to DNA damage and suffers mistakes in replication. ...
Translational Cancer Genomics
The Translational Cancer Genomics team investigate how genetic alterations in cancer contribute to disease and impact on response to therapy.
Programmes and Facilities
We are focused on using single-cell approaches, so called “cell atlas” technologies and understanding human genetics at the cellular level. The ...