National Institutes of Health

arcOGEN (Arthritis Research UK Osteoarthritis Genetics)

arcOGEN was a study that aimed to find genetic determinants of osteoarthritis and elucidate the genetic architecture of the disease.

Archive Page

This page is maintained as a historical record and is no longer being updated.

The collaboration has now ended. This page is being maintained as a historical record of the project and is no longer being updated.

Osteoarthritis is the most common form of arthritis – it affects about 8 million people in the UK and presents major health and economic burdens. There is a considerable genetic component to osteoarthritis: those people with a parent or sibling with the condition are two to three times more likely to develop osteoarthritis than those who don’t.


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