GWAVA - Genome Wide Annotation of VAriants

GWAVA is a tool which aims to predict the functional impact of non-coding genetic variants based on a wide range of annotations of non-coding elements (largely from ENCODE/GENCODE), along with genome-wide properties such as evolutionary conservation and GC-content.

To use GWAVA you can either download the software and necessary annotation files and run it locally, or you can access pre-computed scores and annotations from a webserver with annotations for all known variants (from Ensembl release 70). A plugin for the Ensembl Variant Effect Predictor is also available from the download page.

If you have any problems with or questions about this resource please contact Graham Ritchie.

[Genome Research Limited]

* quick link - http://q.sanger.ac.uk/t5k1cict