Multiple Motif Meta Analysis (M3A)

The Multiple Motif Meta Analysis (M3A) method can be used to identify enriched and de-enriched DNA motifs from a collection of sequences (e.g. enhancers or promoters). Unlike many other methods, M3A relies on an annotated list of motifs which makes it easier to interpret results biologically.

Given a set of sequences (e.g. corresponding to enhancers), and a collection of TF binding motifs (we offer several curated sets), M3A will identify motifs which are significantly enriched or de-enriched.


M3A is used via a web-interface.

Sanger Institute Contributors

Previous contributors

Photo of Dr Martin Hemberg

Dr Martin Hemberg

Former CDF Group Leader

External Contributors

Photo of Naman Jain

Naman Jain