alleleIntegrator searches for allelic imbalances that represent cancer-defining somatic copy number changes to precisely identify single cancer cell transcriptomes.
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alleleIntegrator enables researchers to identify cancer cells in single-cell experiments that explore gene activity and function. It sifts through the data of each cell's protein production to identify imbalances in the amount of different versions of the same protein. These imbalances are the result of cancer-defining changes in DNA that take place over a person's lifetime.
Sanger Institute Contributors
Wellcome Sanger Institute