COMET

COMET (Corrected Overlap and Marginal Enrichment Test) is a computationally efficient method for identifying SNP features (e.g. functional annotation) that are predictive of associated SNPs that are shared between traits, while adjusting for the marginal distributions of the traits.

COMET (Corrected Overlap and Marginal Enrichment Test) is a computationally efficient method for identifying SNP features (e.g. functional annotation) that are predictive of associated SNPs that are shared between traits, while adjusting for the marginal distributions of the traits. COMET also assesses enrichment at the individual trait level. Only summary statistics are required to implement COMET.

Contact

If you need help or have any queries, please contact us using the details below.

If you have any problems running COMET then please contact Jennifer Asimit.


Sanger Institute Contributors

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Dr Jennifer Asimit

MRC Methodology Research Fellow - Statistical Geneticist