Toxoplasma gondii

Toxoplasma gondii is a protozoan parasite which casuses disease in humans and has a very wide host range. It is capable of infecting almost any cell type in any warm-blooded animal.

Data Downloads

This project is ongoing and data for this organism will be made available in due course.

The Sanger Insitute has used high-throughput transcriptome sequencing (mRNA-seq) to determine the transcriptome of T. gondii VEG strain tachyzoites. The goal of this project is to determine differences between T. gondii and the similar parasite Neospora caninum.

The T. gondii genome was sequenced by the J Craig Venter Insitute and is available from ToxoDB.

Bibliography

Common inheritance of chromosome Ia associated with clonal expansion of Toxoplasma gondii.

Khan A, Böhme U, Kelly KA, Adlem E, Brooks K, Simmonds M, Mungall K, Quail MA, Arrowsmith C, Chillingworth T, Churcher C, Harris D, Collins M, Fosker N, Fraser A, Hance Z, Jagels K, Moule S, Murphy L, O'Neil S, Rajandream MA, Saunders D, Seeger K, Whitehead S, Mayr T, Xuan X, Watanabe J, Suzuki Y, Wakaguri H, Sugano S, Sugimoto C, Paulsen I, Mackey AJ, Roos DS, Hall N, Berriman M, Barrell B, Sibley LD and Ajioka JW

Genome research 2006;16;9;1119-25

PUBMED: 16902086; PMC: 1557770; DOI: 10.1101/gr.5318106

Data Use Statement

This sequencing centre plans on publishing the completed and annotated sequences in a peer-reviewed journal as soon as possible. Permission of the principal investigator should be obtained before publishing analyses of the sequence/open reading frames/genes on a chromosome or genome scale. See our data sharing policy.

Sequencing enquiries

Please address all sequencing enquiries to: pathinfo@sanger.ac.uk