Neospora caninum

Neospora caninum is a protozoan parasite of the phylum Apicomplexa that has emerged as a global pathogen of major importance in cattle and dogs. It is estimated to have a nuclear genome size of ~62MB.

Data Downloads

FTP site

BLAST server

The Sanger Institute, in collaboration with the University of Liverpool, has sequenced the genome of the Neospora caninum Liverpool strain to 8x coverage using capillary sequencing. High-thoughput second generation transcriptome sequencing (mRNA-Seq) has been used to improve annotation of the genome sequence and also to study differential expression in the tachyzoite life stage.

Published Genome Data

The N. caninum genome assembly and annotation is available from GeneDB [1].

Bibliography

Characterization and gene expression analysis of the cir multi-gene family of Plasmodium chabaudi chabaudi (AS).

Lawton J, Brugat T, Yan YX, Reid AJ, Böhme U, Otto TD, Pain A, Jackson A, Berriman M, Cunningham D, Preiser P and Langhorne J

BMC genomics 2012;13;125

PUBMED: 22458863; PMC: 3384456; DOI: 10.1186/1471-2164-13-125

Data Use Statement

This sequencing centre plans on publishing the completed and annotated sequences in a peer-reviewed journal as soon as possible. Permission of the principal investigator should be obtained before publishing analyses of the sequence/open reading frames/genes on a chromosome or genome scale. See our data sharing policy.

Sequencing enquiries

Please address all sequencing enquiries to: pathinfo@sanger.ac.uk