Haemonchus contortus

Haemonchus contortus is a highly pathogenic parasitic nematode of that can infect a large number of wild and domesticated ruminant species and is the most economically important parasite of sheep and goats worldwide. Although originally a tropical parasite, it has been disseminated around the world by livestock movement and can now be found as far north as the arctic circle. Adult worms are blood feeders that reside in the abomasum (stomach) and are approximately 2cm in length when mature. They are dioecious with single females typically producing several thousand eggs per day which pass out of the host in faeces and develop to infective larvae on the pasture.

H. contortus is a member of the superfamily trichostrongyloidea (Strongylida) which contains most of the economically important parasitic nematodes of grazing livestock. These parasites cost the global livestock industry billions of dollars per annum in lost production and drug costs. Resistance to all the major anthelmintic classes is now common worldwide often leading to failure of treatment and control. H. contortus is a close relative of the human hookworm species and belongs to the nearest phylogenetic group of parasites to the free-living model nematode Caenorhabditis elegans. This makes it an important model of parasitic nematode biology that is commonly used for experimental studies.

Data Downloads

[John Gilleard]

This is a Wellcome Trust funded project to sequence and analyse the nuclear genome of H. contortus with the goal of producing reference quality genome sequence. We are collaborating with John Gilleard (University of Calgary).

Studies

Haemonchus contortus transcriptome

Sample

Strain

Run Accession

ISE_21dISEERR411602
WRS_21dISEERR411603
CAVR_21dISEERR411604
ISE_L3_4535ISEERR411615
ISE_L3_4535ISEERR411607
ISE_L3_4535ISEERR411612
21d_ISE_ABZISEERR411610
21d_ISE_ABZISEERR411605
21d_ISE_ABZISEERR411613
21d_ISE_DMSOISEERR411606
21d_ISE_DMSOISEERR411611
21d_ISE_DMSOISEERR411614
21d_ISE_1ISEERR411608
21d_ISE_2ISEERR411609
Mhco16_AMHco3(ISE)ERR411616
Mhco5MHco3(ISE)ERR411617
21d_ISE_rep2_207772UnknownERR411618
21d_ISE_rep3_207772UnknownERR411619
eggs1_236476inbred ISEERR229528
eggs2_236476inbred ISEERR229529
eggs3_236476inbred ISEERR229530
L1_1_236476inbred ISEERR229531
L1_2_236476inbred ISEERR229532
L1_3_236476inbred ISEERR229533
L4_1_236476inbred ISEERR229534
L4_2_236476inbred ISEERR229535
L4_3_236476inbred ISEERR229536
AdultF1_236476inbred ISEERR229537
AdultF2_236476inbred ISEERR229538
AdultF3_236476inbred ISEERR229539
AdultM1_236476_2305Inbred ISEERR229540
AdultM2_236476_2305Inbred ISEERR229541
AdultM3_236476_2305Inbred ISEERR229542
BXC1_236476_2292Inbred ISEERR411620
BXC2_236476_2292Inbred ISEERR411621
BXC3_236476_2292Inbred ISEERR411622
EXL3_1_236476_2305Inbred ISEERR229543
EXL3_2_236476_2305Inbred ISEERR229544
EXL3_3_236476_2305Inbred ISEERR229545
SHL3_1_236476_2305Inbred ISEERR229546
SHL3_2_236476_2305Inbred ISEERR229547
SHL3_3_236476_2305Inbred ISEERR229548
gut1_236476_1517MHco3(ISE)ERR229549
gut2_236476_1589MHco3(ISE)ERR229550
gut3_236476_635JMHco3(ISE)ERR229551
F1_ISE_Hcon247373ISEERR411623
F2_ISE_Hcon247373ISEERR411624
F3_ISE_Hcon247373ISEERR411625
F1_CAVR_Hcon247373CAVRERR411626
F2_CAVR_Hcon247373CAVRERR411627
F3_CAVR_Hcon247373CAVRERR411628
F1_WRS_Hcon247373WRSERR411629
F2_WRS_Hcon247373WRSERR411630
F3_WRS_Hcon247373WRSERR411631

Haemonchus contortus BAC pool sequencing

Sample

Strain

Run Accession

HC24_DUnknownERR172683
HC23_DUnknownERR172682
HC22_DUnknownERR172681
HC21_DUnknownERR172680
HC20_DUnknownERR172679
HC19_DUnknownERR172678
HC18_DUnknownERR172677
HC17_DUnknownERR172676
HC16_DUnknownERR172675
HC15_DUnknownERR172674
HC14_DUnknownERR172673
HC13_DUnknownERR172672
HC12_DUnknownERR172671
HC11_DUnknownERR172670
HC10_DUnknownERR172669
HC9_DUnknownERR172668
HC8_DUnknownERR172667
HC7_DUnknownERR172666
HC6_DUnknownERR172665
HC5_DUnknownERR172664
HC4_DUnknownERR172663
HC3_DUnknownERR172662
HC2_DUnknownERR172661
HC1_DUnknownERR172660
HC24_CUnknownERR172659
HC23_CUnknownERR172658
HC22_CUnknownERR172657
HC21_CUnknownERR172656
HC20_CUnknownERR172655
HC19_CUnknownERR172654
HC18_CUnknownERR172653
HC17_CUnknownERR172652
HC16_CUnknownERR172651
HC15_CUnknownERR172650
HC14_CUnknownERR172649
HC13_CUnknownERR172648
HC12_CUnknownERR172647
HC11_CUnknownERR172646
HC10_CUnknownERR172645
HC9_CUnknownERR172644
HC8_CUnknownERR172643
HC7_CUnknownERR172642
HC6_CUnknownERR172641
HC5_CUnknownERR172640
HC4_CUnknownERR172639
HC3_CUnknownERR172638
HC2_CUnknownERR172637
HC1_CUnknownERR172636
HC24_BUnknownERR172635
HC23_BUnknownERR172634
HC22_BUnknownERR172633
HC21_BUnknownERR172632
HC20_BUnknownERR172631
HC19_BUnknownERR172630
HC18_BUnknownERR172629
HC17_BUnknownERR172628
HC16_BUnknownERR172627
HC15_BUnknownERR172626
HC14_BUnknownERR172625
HC13_BUnknownERR172624
HC12_BUnknownERR172623
HC11_BUnknownERR172622
HC10_BUnknownERR172621
HC9_BUnknownERR172620
HC8_BUnknownERR172619
HC7_BUnknownERR172618
HC6_BUnknownERR172617
HC5_BUnknownERR172616
HC4_BUnknownERR172615
HC3_BUnknownERR172614
HC2_BUnknownERR172613
HC24_AUnknownERR172612
HC23_AUnknownERR172611
HC22_AUnknownERR172610
HC21_AUnknownERR172609
HC20_AUnknownERR172608
HC19_AUnknownERR172607
HC18_AUnknownERR172606
HC17_AUnknownERR172605
HC16_AUnknownERR172604
HC15_AUnknownERR172603
HC9_AUnknownERR172597
HC8_AUnknownERR172596
HC7_AUnknownERR172595
HC6_AUnknownERR172594
HC5_AUnknownERR172593
HC4_AUnknownERR172592
HC3_AUnknownERR172591
HC2_AUnknownERR172590
HC14_AUnknownERR172602
HC13_AUnknownERR172601
HC12_AUnknownERR172600
HC11_AUnknownERR172599
HC10_AUnknownERR172598
HC1_AUnknownERR172589

Data Use Statement

This sequencing centre plans on publishing the completed and annotated sequences in a peer-reviewed journal as soon as possible. Permission of the principal investigator should be obtained before publishing analyses of the sequence/open reading frames/genes on a chromosome or genome scale. See our data sharing policy.

Sequencing enquiries

Please address all sequencing enquiries to: pathinfo@sanger.ac.uk

* quick link - http://q.sanger.ac.uk/gk9iwo6l