Echinococcus granulosus

Echinococcus granulosus is a member of the Cyclophyllidea, which comprise the majority of tapeworms that are of medical importance. Adult E. granulosus parasitise the small intestines of dogs and other canids. Larval stages of E. granulosus and the related Taenia solium cause the serious and life-threatening human diseases cystic echinococcosis and neurocysticercosis, respectively. E. granulosus has a worldwide distribution.

Data Downloads

FTP site

BLAST server

The genome sequence of E. granulosus will be used in comparative studies with the related Echinococcus multilocularis, for which a reference quality genome is being produced.

This work is being done in collaboration with Cecilia Fernandez from the Universidad de la República, Montevideo, Uruguay.

Bibliography

The genomes of four tapeworm species reveal adaptations to parasitism.

Tsai IJ, Zarowiecki M, Holroyd N, Garciarrubio A, Sánchez-Flores A, Brooks KL, Tracey A, Bobes RJ, Fragoso G, Sciutto E, Aslett M, Beasley H, Bennett HM, Cai X, Camicia F, Clark R, Cucher M, De Silva N, Day TA, Deplazes P, Estrada K, Fernández C, Holland PWH, Hou J, Hu S, Huckvale T, Hung SS, Kamenetzky L, Keane JA, Kiss F, Koziol U, Lambert O, Liu K, Luo X, Luo Y, Macchiaroli N, Nichol S, Paps J, Parkinson J, Pouchkina-Stantcheva N, Riddiford N, Rosenzvit M, Salinas G, Wasmuth JD, Zamanian M, Zheng Y, Taenia solium Genome Consortium, Cai J, Soberón X, Olson PD, Laclette JP, Brehm K and Berriman M

Nature 2013;496;7443;57-63

PUBMED: 23485966; PMC: 3964345; DOI: 10.1038/nature12031

Data Use Statement

This sequencing centre plans on publishing the completed and annotated sequences in a peer-reviewed journal as soon as possible. Permission of the principal investigator should be obtained before publishing analyses of the sequence/open reading frames/genes on a chromosome or genome scale. See our data sharing policy.

Sequencing enquiries

Please address all sequencing enquiries to: pathinfo@sanger.ac.uk