Echinococcus granulosus is a member of the Cyclophyllidea, which comprise the majority of tapeworms that are of medical importance. Adult E. granulosus parasitise the small intestines of dogs and other canids. Larval stages of E. granulosus and the related Taenia solium cause the serious and life-threatening human diseases cystic echinococcosis and neurocysticercosis, respectively. E. granulosus has a worldwide distribution.
The genome sequence of E. granulosus will be used in comparative studies with the related Echinococcus multilocularis, for which a reference quality genome is being produced.
This work is being done in collaboration with Cecilia Fernandez from the Universidad de la República, Montevideo, Uruguay.
The genomes of four tapeworm species reveal adaptations to parasitism.
PUBMED: 23485966; PMC: 3964345; DOI: 10.1038/nature12031
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