C. elegans is a free-living nematode which is widely used as a model organism. The C. elegans genome has been fully sequenced and is therefore a useful tool to test new approaches in helminth genome sequencing.
The essentially complete genome sequence of Caenorhabditis elegans was published in 1998 after joint sequencing project by the Wellcome Sanger Institute and Washington University School of Medicine in St. Louis. It continues to be maintained and curated by both institutes.
The genome sequence of C elegans (along with that of many other nematodes) is hosted by the WormBase database. WormBase extends beyond the genomic sequence, integrating experimental results with extensively annotated views of the genome. The WormBase Consortium continues to expand the biological scope and utility of the resource with the inclusion of large-scale genomic analyses, through active data and literature curation, through new analysis and visualization tools, and through refinement of the user interface.
C. elegans is being used to test a number of amplification approaches for use in parasitic helminth genome sequencing.
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.) 1998;282;5396;2012-8
Data Use Statement
This sequencing centre plans on publishing the completed and annotated sequences in a peer-reviewed journal as soon as possible. Permission of the principal investigator should be obtained before publishing analyses of the sequence/open reading frames/genes on a chromosome or genome scale. See our data sharing policy.
Please address all sequencing enquiries to: firstname.lastname@example.org