Tropheryma whipplei

Tropheryma whipplei is a Gram +ve human pathogen that is the causative agent of Whipple's disease.

Data Downloads

The Sanger Institute has published the sequence of the genome of T. whipplei strain TW08/27 in collaboration with Prof. David Relman and Dr. Matthias Maiwald of Stanford University, USA and Prof. Mark Pallen of the Division of Immunity and Infection, University of Birmingham, UK.

Published Genome Data

We have determined the genome sequence of Tropheryma whipplei. The genome is 925,938 bp long, with a G+C content of 46.3%, and is predicted to encode 784 proteins. The sequence has been submitted to EMBL/GenBank with the accession number BX072543.

Shotgun and assembly data from this project are available from our ftp site.


  • Sequencing and analysis of the genome of the Whipple's disease bacterium Tropheryma whipplei.

    Bentley SD, Maiwald M, Murphy LD, Pallen MJ, Yeats CA, Dover LG, Norbertczak HT, Besra GS, Quail MA, Harris DE, von Herbay A, Goble A, Rutter S, Squares R, Squares S, Barrell BG, Parkhill J and Relman DA

    Lancet (London, England) 2003;361;9358;637-44

Data Use Statement

This sequencing centre plans on publishing the completed and annotated sequences in a peer-reviewed journal as soon as possible. Permission of the principal investigator should be obtained before publishing analyses of the sequence/open reading frames/genes on a chromosome or genome scale. See our data sharing policy.

Sequencing enquiries

Please address all sequencing enquiries to: