Burkholderia cenocepacia (formerly Burkholderia cepacia genomovar III, and before that Pseudomonas cepacia) is a Gram negative bacterium which is ubiquitous in the environment and may cause a number of diseases in plants. Human infection can be caused by B. cepacia, especially in patients with cystic fibrosis and chronic granulomatous disease, and is often fatal.
The Sanger Institute has completed the sequencing of and published the 8.06 Mb genome of Burkholderia cenocepacia strain J2315, in collaboration with Dr. Eshwar Mahenthiralingham of the School of Biosciences, Cardiff University, Prof. John Govan of the Department of Medical Microbiology, University of Edinburgh, Prof. C.A. Hart of the Department of Medical Microbiology, University of Liverpool, and Prof. Peter Vandamme of the Laboratorium voor Microbiologie, Universiteit Gent, Belgium.
Note that B. cenocepacia J2315 has recently been renamed from B. cepacia J2315
Published Genome Data
The sequenced strain, J2315, is a genomovar III strain of the ET12 lineage, and is the index strain for transmission of this strain among CF patients in the UK. Strain J2315 has been deposited as LMG 16656 in the Belgium Coordinated Collection of Microorganisms.
The sequence and annotation of the Burkholderia cenocepacia strain J2315 genome have been deposited in the EMBL database under accession numbers AM747720, AM747721, AM747722 and AM747723
Shotgun and assembly data from this project are available from our FTP site.
StudiesUnable to read file: inc/burkholderia-cenocepacia.inc
The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of cystic fibrosis patients.
Journal of bacteriology 2008;191;1;261-77
PUBMED: 18931103; PMC: 2612433; DOI: 10.1128/JB.01230-08
Burkholderia cenocepacia sp. nov.--a new twist to an old story.
Research in microbiology 2003;154;2;91-6
PUBMED: 12648723; DOI: 10.1016/S0923-2508(03)00026-3
Data Use Statement
This sequencing centre plans on publishing the completed and annotated sequences in a peer-reviewed journal as soon as possible. Permission of the principal investigator should be obtained before publishing analyses of the sequence/open reading frames/genes on a chromosome or genome scale. See our data sharing policy.
Please address all sequencing enquiries to: firstname.lastname@example.org