We seek to explore the vast cellular diversity in the human brain using large-scale spatial transcriptomics, imaging and functional screens.
Connecting human development and disease
Our research sits at the interface of cancer genomics and single cell transcriptomics. Our aim is to unravel the identity and ...
Cellular Genetics Informatics
Our team provides efficient access to cutting-edge analysis methods, environments and pipelines for Cellular Genetics programme, which leads and is involved ...
Cellular Genetics Wet Lab Support Team
We enable the Institute to deliver its world-leading, cutting-edge cell atlassing research for the Human Cell Atlas initiative within the Cellular ...
Single-cell multi-omics tissue mapping and organoid-based disease modeling
We work on a range of tissues and employ multiple cutting-edge tools such as CRISPR perturbation and organoid modeling.
Our research is focused on understanding what type of immune cells live within different organs in humans, and how the special ...
Cellular Genetics Programme
The team’s research applies disruptive cutting-edge techniques to study the genomics of immune cell populations at single-cell resolution and uses ...
Human Cell Atlas - Executive Office (UK)
The HCA Executive Office, in the UK, is based at the Wellcome Sanger Institute, and works with regional offices in the ...
Single cell genomics
John Marioni's group develop computational and statistical tools to exploit high-throughput genomics data to understand the regulation of gene expression ...
Stegle and Theis Group
Cellular Genetics Programme
We aim to leverage machine learning in the context of single cell genomics to provide a true model-based understanding of the ...
Gene expression genomics
We use cutting edge single cell genomics technologies and computational methods to understand genes, proteins and cells in human health and ...
Epigenetic mechanisms in health and disease
Adrian's group is investigating "The function of long non-coding RNAs originating at CpG island promoters" and "The effects of ...
Genomics of gene regulation
Gene expression involves the transformation of genetic information encoded in DNA sequence into a gene product, such as a protein. Regulation ...
Quantitative models of gene expression
The Hemberg group is interested in developing quantitative models of gene expression. Our approach is theoretical and we strive to develop ...
The Vallier laboratory studies the basic mechanisms controlling differentiation of human pluripotent cells into pancreas, lung, gut and liver cells.
Obesity-associated Metabolic Complications
We aim to learn why being obese causes metabolic and cardiovascular problems and to provide the rational for mechanistically driven therapeutic ...
Related International Fellows and Honorary Faculty
Dr Annettee Nakimuli
Annettee Nakimuli is a leading maternal health researcher based in Uganda, focused primarily on investigating the aetiology, treatment, prevention and long ...
Cellular Genetics Portals
Open-access data portals
The Cellular Genetics Programme is committed to making cell atlasing data analysis and visualisation tools available to the scientific community
Cellular Genetics Software
Open access tools
Computational tools developed by the research groups and scientific teams of the Cellular Genetics Programme
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Uterus study is important step towards understanding diseases that affect one third of women
The study's organoid-based techniques provide a sophisticated model of endometrial function and will form a blueprint for discovering how other ...
3 Nov 2021
Sanger researchers to tackle deadly brain cancer with ‘tissue time machine’
Sanger Institute scientists are starting a new project that will integrate information from spatial transcriptomics with single-cell RNA and DNA sequencing, ...