The Tree of Life Programme investigates the diversity of complex organisms (eukaryotes) found in the UK through sequencing and cellular technologies. It also compares and contrasts species' genome sequences to unlock insights into evolution and conservation.
The Sanger Institute is developing a major programme in biological diversity genome sequencing across the tree of life. One of the driver projects for this is to play a major collaborative role in the international Vertebrate Genomes Project (VGP).
The following Sanger Institute research groups are contributing to the Tree of Life Programme
Some mosquitoes are better at transmitting malaria parasites than others. Likewise, some parasites are better at infecting mosquitoes than others. Our research group uses genomics to investigate these phenomena. We have two major research themes we are working on, described in more detail below.
The Genome Reference Informatics Team analyses genome assemblies to reveal and correct quality issues and to identify and add variation. It forms the Sanger division of the Genome Reference Consortium and the Vertebrate Genomes Project.
All life is linked by the common thread of DNA, modified through evolution. We use whole genome sequences to explore the patterns and processes that generate genomic and biotic diversity across the Tree of Life.
Red and grey squirrel genomes could hold the key to the survival of reds in Britain and Ireland