The immune system must maintain a delicate balance; it should be sensitive enough to eliminate invading pathogens while being tolerant of the body's own cells. Immune-mediated diseases can occur when the immune system gets this balance wrong and attacks cells and substances typically found in the body. These diseases are known to "run in families", suggesting that inherited genetic risk factors play a role in susceptibility. The aim of our research is to improve our understanding of immune-mediated diseases by identifying and functionally characterising the specific regions of the genome that influence disease risk, progression and response to therapy. We undertake both computational and wet lab research in order to achieve these goals. The Anderson Lab currently consists of 18 people from a diverse range of backgrounds, including genetics, mathematics, medicine, computer science, cell biology and immunology.