Dr Elizabeth Goode
Clinical PhD Student
I am a Gastroenterologist and Hepatologist with an interest immune-mediated liver diseases. As a Wellcome trust clincial PhD fellow, my current research focuses on using genetic risk associations for primary sclerosing cholangitis (PSC) to understand the genes, cell types and biological mechanisms causing this debilitating disease.
I qualified as a medical doctor in 2009 from Imperial College, London with an intercalated BSc in Medical Sciences with Haematology. My undergraduate research focused on deciphering the function of N-linked glycosylation sites on the synthesis and function of von Willebrand Factor, a blood glycoprotein with an essential role in haemostasis. In 2011, I commenced an Academic Clinical Fellowship in Gastroenterology, and quickly developed and interest in immune-mediated liver diseases, specifically primary sclerosing cholangitis (PSC). Alongside my clinical training in Gastroenterology and Hepatology, I spent several years working with the UK-PSC Consortium (http://www.uk-psc.com/) to develop a risk scoring system for adverse patient outcomes, using clinical phenotype data from 1000 patient recruited to the UK-PSC Genetics Study. The collaboration between UK-PSC and the Anderson group led to my joining the Anderson team in 2016 as a Wellcome Trust Clinical PhD Fellow. Here, my work focuses on furthering our understanding of genetic risk variants through RNA sequencing of PSC-relevant tissues. My extra-medical interests include running around after my young daughter, playing the violin and contesting parking penalty notices.