- Immunogenomics - Immune responses against infection. Using genomics, imaging and computational tools, we seek to understand the checkpoint mechanisms that ensure tailored immune responses against different infections in distinct tissues. Our long-term goal is to understand the intracellular and extracellular mechanisms that shape the architecture of the immune response against infection.
- Reproductive atlas - Reconstructing dynamic maps of reproductive organs. As part of the Developmental Atlas in partnership with the Human Cell atlas, we are seeking to produce a comprehensive 3D cellular map of the reproductive system.
- Cellular networks - Cell-cell communication. We aim to create an interactome map that will help us understand the basic mechanisms of cellular responses and functions, by mapping all interactions between the receptors on cells' surfaces and the ligands they bind, along with their downstream signals. To acheive this we are developing new approaches using single-cell and spatial transcriptomic data.
Postdoctoral fellow positions
We encourage potential postdocs to apply for independent funding. We are happy to brainstorm ideas and help with the development of the proposal.
To apply for a PhD position in our group, please refer to the Wellcome Sanger Institute’s PhD Programme
More about the group's research
To find out more, please click on 'Read More' below.