The major theme of our research is the study of genome variation: naturally occurring and engineered, inherited and somatic, in humans, pathogens, human cells and mice.

Our science is organised into five Scientific Programmes, each defining a major area of research with a particular biological, disease or analytic focus. In all cases, the studies provide insights into human, pathogen, cellular evolution, the phenotypic and hence biological consequences of genome variation and the processes which cause mutations.

We aim to carry out studies that are of a design and scale that cannot be conducted in most biomedical research institutes.

In 2018 the Infection Genomics and Malaria Programmes joined to form Parasites and Microbes.

Two previous programmes - Computational Genomics and Mouse and Zebrafish - ran until October 2016.

Sanger Institute Research Publications

Since 1992, the Sanger Institute has published papers in some of the most prestigious scientific journals, covering genetics and genomics in wide range of biological fields. Our aim is to deliver research that will transform biology and improve healthcare.

Recent Discoveries