Rahbari Group
Cancer predisposition and Ageing
Our group aims to provide a detailed description of the genetic changes in normal and precancerous tissues, and to understand how mutations acquired during ageing may contribute to the germline predisposition to cancer for future offspring.
During the natural process of ageing, somatic mutations accumulate in our genome and can cause cancer and cancer prediposition. However, little is known about mutagenesis or factors that influence rates of accumulation of mutations in normal tissue and their impact.
Our group aims to provide a detailed description of the genetic changes in normal and precancerous tissues, and to understand how mutations acquired during ageing may contribute to the germline predisposition to cancer for future offspring.
Core team

Sean Laidlaw
Bioinformatician

Dr Thomas RW Oliver
PhD Student

Mr Rashesh Sanghvi, MS
Senior Bioinformatician
Wellcome Sanger Institute