Rashesh is a senior bioinformatician in the Rahbari group focusing on somatic mutations acquired overtime during aging. His current focus is on somatic mutations and clonal dynamics in normal Testes.
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Mutational signatures in esophageal squamous cell carcinoma from eight countries with varying incidence
https://www.nature.com/articles/s41588-021-00928-6
So excited to announce that our latest work on somatic mutations in #liverdisease, led by Stanley Ng has been published in @Nature. Livers from patients with #NAFLD or ARLD contain recurrent acquired mutations in 6 genes and 1 lncRNA. #livertwitter http://disq.us/t/41xr1fr
Out today @Nature! Human tissues accumulate cancer-driver mutations with age, yet tumor formation remains rare, why!? We show that mutant clones in the normal epithelium can have a tumor-protective role by outcompeting and eliminating nascent tumors. https://www.nature.com/articles/s41586-021-03965-7
