New Pipeline Group (NPG)
DNA Pipelines Informatics
NPG is responsible for DNA Pipelines's production informatics analysis pipelines, Illumina sequencing QC tools and expertise, and internal archiving of data products.
The NPG team liaise with production teams and faculty informatics (the customer element directly using the product) to learn of desired features for processing and common best practices. Senior DNA Pipelines management pass to NPG expected changes in the nature of the product and demand e.g. new instruments, new instrument types and new projects with expected throughput and processing requirements.
From these, small requirements are considered and typically a solution proposed, provided and reviewed by a subset of the NPG team. Larger requirements are dealt with as projects. When appropriate we’ll contact Wellcome Sanger Institute Systems asking for advice, review, new services or enhancements.
NPG reviews continuously its systems with an eye to product trends and implements long rolling projects to accommodate them. e.g. adoption of BAM format based analysis pipelines (addressing provenance records in a multiple path analysis suite, and reducing IO) and increased data streaming between analysis tools (to reduce IO requirements, avoid the need for a high performance file-system, allow for an easily scalable system).
The NPG team has to maintain informatics, Illumina sequencing, and genotyping knowledge sufficient to anticipate and understand DNA Pipelines customer requirements so that requests can be anticipated, evaluated and rejected or implemented appropriately.
Cellular Genetics Informatics
Our team provides efficient access to cutting-edge analysis methods, environments and pipelines for Cellular Genetics programme, which leads and is involved ...
NPG provide interfaces for sequencing run creation and sequencing run QC to the operations teams. We also provide training and advice ...
DNA Pipelines Research and Development
DNA Pipelines Development
The latest and greatest stuff from R&D often requires custom analysis or changes to our pipelines and services.
High Performance Algorithm Group (HPAG)
HPA has created tools which are essential components of NPG's current analysis pipelines and leads on developing and testing ...
Human Genetics Informatics (HGI)
Human Genetics Informatics (HGI) supports the scientific aims of the Human Genetics programme by developing and operating computational analysis workflows, managing ...
Informatics Support Group
High Performance Computing
NPG are reliant on the Sanger systems teams for providing solid compute and storage.
Production Software Development
LIMS compute and infrastructure
We work closely with PSD as their systems provide us with all the LIMS information required to run our analysis pipelines ...
Sequence Analysis and Management (SAM)
The SAM team is responsible for archival of the data produced by NPG to external repositories, typically the EGA, ENA or ...