High Performance Algorithm Group (HPAG)
- Development of genome assembly tools using second and third generation sequencing data
- Efficient algorithms for detecting structural variations from single molecule sequencing data
- Detection of segmental duplications from kmer distribution profiles
Dr Zemin Ning
Senior Scientific Manager
Zemin oversees the activities of the group. He interacts with both internal and external collaborators on various projects, while providing technical guidance and support for the group members. He is also actively involved in algorithm development and code programming.
An effective tool, based on the Pattern Growth algorithm to detect breakpoints of large indels.
SMALT efficiently aligns DNA sequencing reads with a reference genome.Reads from a wide range of sequencing platforms, for example Illumina, ...
SMIS ( Single Molecular Integrative Scaffolding ): an assembly pipeline to improve genome scaffolding using Oxford Nanopore or PacBio long reads.
SSAHA ( Sequence Search and Alignment by Hashing Algorithm ) is a software tool for very fast matching and alignment of DNA sequences.
DNA Pipelines Research and Development
DNA Pipelines Development
The DNA Pipelines Research and Development group is the entry point for new technologies to the Institute, especially sequencing instruments. The ...
Genome Reference Informatics Team
Tree of Life Programme
Collaborate on the generation of zebrafish assemblies.
New Pipeline Group (NPG)
HPA has created tools which are essential components of NPG's current analysis pipelines and leads on developing and testing software ...
We work with the following groups
Work with Dr Elizabeth Murchison on Tasminan Devil pan-cancer genome project.