The Genome Reference Informatics Team analyses genome assemblies to reveal and correct quality issues and to identify and add variation. The team consists of Senior Bioinformaticians and Senior Computer Biologists to cover software development, data analysis and genome curation. Besides comissioning sequencing and generation of genome data (e.g. optical mapping) and assembly generation, we develop bespoke software like gEVAL to identify and visualize genome assembly issues. This is used by our curators to resolve those issues through changes or additions to the assemblies, thereby vastly improving assembly accuracy.
We are evaluating and improving assemblies as members of the Darwin Tree of Life Project (see also here), the Vertebrate Genome Project, the Human Pangenome Project, the Genome Reference Consortium and others. We work closely with our consortium partners and other collaborators to ensure access to the latest data and analyses. Assembly improvements are submitted to INSDC on a regular schedule.