I am a Paediatrician Scientist and Group Leader working across Cellular Genetics and Cancer. I am broadly interested in the developmental origins of cancer, especially of childhood cancer. To that end we combine cutting single cell transcriptomics with cancer genomics.
The International Human Cell Atlas initiative aims to create comprehensive reference maps of all human cells—the fundamental units of life—as a basis for both understanding human health and diagnosing, monitoring, and treating disease.
Programmes, Associate Research Programmes and Facilities
The Cancer, Ageing and Somatic Mutation Programme seeks to provide leadership in data aggregation and informatics innovation, developing high-throughput cellular models of cancer for genome-wide functional screens and drug testing, and exploring basic scientific questions about the role somatic mutation plays in clonal evolution, ageing and development.
We are focused on using single-cell approaches, so called “cell atlas” technologies and understanding human genetics at the cellular level. The team combine cutting-edge techniques in wet and dry lab and are applying these methodologies for further understanding of human health, development and disease.
The Vento Lab uses genomics and computational tools to reconstruct immune environments. The main areas of focus are: Immunogenomics - Immune responses against infection, Reproductive atlas - Reconstructing dynamic maps of reproductive organs, and Cellular networks - Cell-cell communication