I aim to understand biological phenomena through mathematical/statistical modeling. Currently I'm working on a novel statistical approach that uses a pairwise hierarchical model incorporating a Mendelian Randomisation technique to map causal regulatory interactions in the human genome.
Fine-mapping cellular QTLs with RASQUAL and ATAC-seq.
Nature genetics 2016;48;2;206-13
Genetic background drives transcriptional variation in human induced pluripotent stem cells.
PLoS genetics 2014;10;6;e1004432
Haplotypes with copy number and single nucleotide polymorphisms in CYP2A6 locus are associated with smoking quantity in a Japanese population.
PloS one 2012;7;9;e44507
PlatinumCNV: a Bayesian Gaussian mixture model for genotyping copy number polymorphisms using SNP array signal intensity data.
Genetic epidemiology 2011;35;8;831-44