Dr Caroline Durrant | Postdoctoral Fellow

This person is a member of Sanger Institute Alumni.

Durrant, Caroline

I am currently working on the population genetics of various parasites affecting human health, in particular Leishmania and Guinea worm. I use whole-genome sequencing data of parasite genomes to understand the genetic population structure of the parasite. In the past, I have worked on method development for quantitative trait locus mapping using inferred haplotypes and for disease gene mapping in population-based association studies.

Publications

  • Evaluation of conjunctival swab sampling in the diagnosis of canine leishmaniasis: A two-year follow-up study in Çukurova Plain, Turkey.

    Karakuş M, Töz S, Ertabaklar H, Paşa S, Atasoy A et al.

    Veterinary parasitology 2015;214;3-4;295-302

  • Mosaic aneuploidy in Leishmania: the perspective of whole genome sequencing.

    Dujardin JC, Mannaert A, Durrant C and Cotton JA

    Trends in parasitology 2014;30;12;554-5

  • Collaborative Cross mice and their power to map host susceptibility to Aspergillus fumigatus infection.

    Durrant C, Tayem H, Yalcin B, Cleak J, Goodstadt L et al.

    Genome research 2011;21;8;1239-48

  • Bayesian quantitative trait locus mapping using inferred haplotypes.

    Durrant C and Mott R

    Genetics 2010;184;3;839-52

  • A Multiparent Advanced Generation Inter-Cross to fine-map quantitative traits in Arabidopsis thaliana.

    Kover PX, Valdar W, Trakalo J, Scarcelli N, Ehrenreich IM et al.

    PLoS genetics 2009;5;7;e1000551

  • Gene X environment interactions at the serotonin transporter locus.

    Munafò MR, Durrant C, Lewis G and Flint J

    Biological psychiatry 2009;65;3;211-9

  • Linkage disequilibrium mapping via cladistic analysis of single-nucleotide polymorphism haplotypes.

    Durrant C, Zondervan KT, Cardon LR, Hunt S, Deloukas P and Morris AP

    American journal of human genetics 2004;75;1;35-43

  • Evaluation of conjunctival swab sampling in the diagnosis of canine leishmaniasis: A two-year follow-up study in Çukurova Plain, Turkey.

    Karakuş M, Töz S, Ertabaklar H, Paşa S, Atasoy A et al.

    Veterinary parasitology 2015;214;3-4;295-302

  • Mosaic aneuploidy in Leishmania: the perspective of whole genome sequencing.

    Dujardin JC, Mannaert A, Durrant C and Cotton JA

    Trends in parasitology 2014;30;12;554-5

  • Host susceptibility to periodontitis: mapping murine genomic regions.

    Shusterman A, Durrant C, Mott R, Polak D, Schaefer A et al.

    Journal of dental research 2013;92;5;438-43

  • Bioinformatics tools and database resources for systems genetics analysis in mice--a short review and an evaluation of future needs.

    Durrant C, Swertz MA, Alberts R, Arends D, Möller S et al.

    Briefings in bioinformatics 2012;13;2;135-42

  • The genome architecture of the Collaborative Cross mouse genetic reference population.

    Collaborative Cross Consortium

    Genetics 2012;190;2;389-401

  • Collaborative Cross mice and their power to map host susceptibility to Aspergillus fumigatus infection.

    Durrant C, Tayem H, Yalcin B, Cleak J, Goodstadt L et al.

    Genome research 2011;21;8;1239-48

  • Genetic analysis of complex traits in the emerging Collaborative Cross.

    Aylor DL, Valdar W, Foulds-Mathes W, Buus RJ, Verdugo RA et al.

    Genome research 2011;21;8;1213-22

  • Pervasive haplotypic variation in the spliceo-transcriptome of the human major histocompatibility complex.

    Vandiedonck C, Taylor MS, Lockstone HE, Plant K, Taylor JM et al.

    Genome research 2011;21;7;1042-54

  • The effect of genome-wide association scan quality control on imputation outcome for common variants.

    Southam L, Panoutsopoulou K, Rayner NW, Chapman K, Durrant C et al.

    European journal of human genetics : EJHG 2011;19;5;610-4

  • A Multiparent Advanced Generation Inter-Cross to fine-map quantitative traits in Arabidopsis thaliana.

    Kover PX, Valdar W, Trakalo J, Scarcelli N, Ehrenreich IM et al.

    PLoS genetics 2009;5;7;e1000551

  • Gene X environment interactions at the serotonin transporter locus.

    Munafò MR, Durrant C, Lewis G and Flint J

    Biological psychiatry 2009;65;3;211-9

  • Efficiency and consistency of haplotype tagging of dense SNP maps in multiple samples.

    Ke X, Durrant C, Morris AP, Hunt S, Bentley DR et al.

    Human molecular genetics 2004;13;21;2557-65

  • Linkage disequilibrium mapping via cladistic analysis of single-nucleotide polymorphism haplotypes.

    Durrant C, Zondervan KT, Cardon LR, Hunt S, Deloukas P and Morris AP

    American journal of human genetics 2004;75;1;35-43

Durrant, Caroline
Caroline's Timeline
2013

Started work as a post-doc at the Sanger Institute, in Dr Matt Berriman's group

2009

Started a post-doc at the Wellcome Trust Centre for Human Genetics, University of Oxford

2005

MRC Training Fellowship in Bioinformatics in the Wellcome Trust Centre for Human Genetics, University of Oxford

2002

DPhil in Statistical Genetics, University of Oxford

2001

MSc in Quantitative Genetics and Genome Analysis, University of Edinburgh

1997

MMath undergraduate degree in mathematics, St Peter's College, University of Oxford