Humans originated in Africa, yet our understanding of African genetic variation is limited, and so this forms one focus of our current work. We also investigate how our ancestors expanded out of Africa into the Middle East and as far as Australia around 50,000 years ago, and how we adapted to the diverse environments including high altitudes in the Himalayas. We explore the insights that natural variation can provide into gene function, and model a few of the advantageous adaptations in mice or cell lines in order to understand the functional changes that were beneficial.
Human Genetics Administration
The Human Genetics Administration comprises a five strong team that provides comprehensive support for the smooth running of the Human Genetics ...