Pregnancy Outcome Prediction Study 2 (POPs2)

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We tackle some of the most difficult challenges in genomic research. This demands science at scale; a visionary and creative approach to research that pushes the boundaries of our understanding in ever new and exciting ways.
About Us
We tackle some of the most difficult challenges in genomic research. This demands science at scale; a visionary and creative approach to research that pushes the boundaries of our understanding in ever new and exciting ways.
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Pregnancy Outcome Prediction Study 2 (POPs2)

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Interactive web portal

Gene Expression Portal: pops2.sanger.ac.uk.

This web portal accompanies the manuscript Maternal immune gene expression trajectories and dynamic genetic regulation throughout pregnancy (medRxiv 2026).

The portal allows exploration of gene expression dynamics across pregnancy, including:

Differential gene expression
Differential variance / heteroskedasticity
Finemapped eQTL effects
eQTL colocalization with GWAS
eQTL interaction effects over time

Sanger Institute Contributors

Photo of Mr Sendu Bala

Mr Sendu Bala

Principle Software Developer

Photo of Dr Katie Burnham

Dr Katie Burnham

Senior Staff Scientist

Photo of Dr Emma Davenport

Dr Emma Davenport

Group Leader

Photo of Sophie Hoffman

Sophie Hoffman

PhD Student

Photo of Dr Mark Thomas

Dr Mark Thomas

Principal Bioinformatician

Previous contributors

Photo of Vivek Iyer

Vivek Iyer

Human Genetics Informatics Team Lead

External Contributors

Photo of Professor Gordon Smith

Professor Gordon Smith

University of Cambridge

Photo of Professor Steve Charnock-Jones

Professor Steve Charnock-Jones

University of Cambridge