Staff PhD and MPhil theses in pdf format
Staff PhD theses can be download here. The first link goes to a directory containing a set of PDF files of the thesis, the second a compressed TAR file of these pdfs.
PhD Theses
Title | Author | Year | Thesis |
---|---|---|---|
Genetic studies of cardiometabolic traits | Riveros Mckay Aguilera, Fernando | 2018 | |
Identification and Characterisation of Regulatory Elements on Human Chromosome 20q12-13.2 | Akan, Pelin | 2006 | |
Regulation of gene expression in macrophage immune response | Alasoo, Kaur | 2016 | |
Signatures of Mutational Processes in Human Cancer | Alexandrov, Ludmil | 2014 | |
Integrated approaches to elucidate the genetic architecture of congenital heart defects | Al Turki, Saeed | 2013 | |
Simian Immunodeficiency Virus Infection of CD4+ T Cell Subsets and Its Impact on B Cell Responses in Early Infection | Archer, Eva Jacqueline | 2016 | |
De novo assembly of the var multi-gene family in clinical samples of Plasmodium falciparum | Assefa, Sammy | 2013 | |
Studies of the effects of promoter sequence variation on gene expression in human chromosome 22 | Bacha, Jamil | 2006 | |
High-throughput Experimental and Computational Studies of Bacterial Evolution | Barquist, Lars | 2013 | |
Gene identification and characterisation on the human X chromosome | Barrett, Ian | 2004 | |
Analysing the B-cell repertoire: Investigating B-cell population dynamics in health and disease. | Bashford-Rogers, Rachael | 2014 | |
Genomic insights into the human population history of Australia and New Guinea | Bergström, Anders | 2017 | |
The evolution of functional non-coding DNA in humans | Bird, Christine | 2010 | Not available |
Sequence alignment in bioinformatics. | Birney, Ewan | 2000 | Not available |
Survey of RNA editing in the human brain | Blow, Matthew J | 2004 | |
Development of computational methods for analysing proteomic data for genome annotation | Brosch, Markus | 2009 | |
Evolutionary Genomics of Pathogenic Mycobacteria | Bryant, Josephine M | 2014 | |
Mechanisms of change in protein architecture | Buljan, Marija | 2010 | |
Rearrangement breakpoints and viral integration sites in the human genome | Burford, Deborah | 2007 | |
Uncovering the role of common and rare variants in migraine | Calafato, Stella | 2012 | |
Identifying and modelling genes that are associated with rare developmental disorders | Carss, Keren | 2014 | |
Evolution of Streptococcus pneumoniae during carriage | Chewapreecha, Claire | 2014 | |
Genetics of the anticoagulant drug warfarin | Chen, Yen-Yu (Leslie) | 2007 | |
The role of transcription factor GATA6 in the development of the human pancreas | Chia, Crystal Ying | 2017 | |
Physical mapping on the human X chromosome and its application to the positional cloning of the XLP gene | Coffey, Alison J | 2000 | Not available |
Protein Domains: New methods for detection and evolutionary analysis | Coin, Lachlan | 2005 | |
The physical map of the genome of Caenorhabditis elegans | Coulson, Alan | 1994 | Not available |
Functional and evolutionary analyses of pneumococcal genome variation | Croucher, Nicholas | 2011 | |
Role of Synapse-Associated Protein 102 in Postsynaptic Signalling, Synaptic Plasticity and Learning | Cuthbert, Peter | 2005 | |
The diversity of disease-causing and environmental Legionella pneumophila | David, Sophia | 2016 | |
Generation of a murine ES cell system deficient in microRNA processing for the identification of microRNA targets | Davis, Matthew | 2009 | |
Chromosomal imbalances in colorectal cancer | Davison, Eleanor | 2004 | Not available |
Understanding inflammatory bowel disease using high-throughput sequencing | de Lange, Katrina Melanie | 2017 | |
The Intra-Tumour Heterogeneity Landscape of Human Cancers | Dentro, Stefan Christiaan | 2017 | |
The SCL Gene and Transcriptional Control of Haematopoiesis | Dhami, Pawandeep | 2005 | |
Development of Chromatin Immuniprecipitation Microarray Technology for the Identification of Regulatory Elements in the Human Genome | Dillon, Shane | 2008 | |
The role of regulatory variation in sculpting gene expression across human populations and cell types | Dimas, Antigone | 2009 | |
The Genetics of Cellular Phenotypes | Ding, Zhihao | 2014 | |
Motif based computational identification of protein subcellular localisation | Dogruel, Mutlu | 2008 | |
Computational localization of promoters and transcription start sites in mammalian genomes | Down, Thomas | 2003 | |
Studies on the development and organisation of the nervous system of Caenorhabditis elegans | Durbin, Richard | 1987 | |
An Analysis of Transcript Variation in Human Xp11.23 | Eades, Tamsin L | 2005 | |
Classification of protein domain families for genomic sequence analysis | Erik, Sonnhammer | 1996 | Not available |
Drivers of melanoma susceptibility | Robles Espinoza, Carla Daniela | 2014 | |
Investigating the Role of Interferon-Inducible Transmembrane 3 (IFITM3) in Infection. | Everitt, Aaron | 2013 | |
Genetic Studies of Syndromes of Severe Insulin Resistance and Type 2 Diabetes: a candidate gene approach | Fawcett, Katherine | 2008 | |
High-throughput reverse genetic screening in Plasmodium berghei using barcode sequencing | Batista Gomes, Ana Rita | 2014 | |
Graphical pangenomics | Garrison, Erik Peter | 2018 | |
Understanding human disease using high-throughput sequencing | Goncalves Serra, Eva | 2016 | |
Structural, functional and comparative studies of human chromosome 22q13.31 | Goward, Melanie | 2002 | |
Chromosome 1 map, sequence and variation | Gregory, Simon | 2003 | |
A Study of Molecular Synergy and Clonal Evolution in Haematopoietic Malignancies | Grove, Carolyn | 2014 | |
Recessive genetic screen for mismatch repair components in BLM-deficient ES cells | Guo, Ge | 2004 | |
Finding genes involved in corneal endothelial dystrophies linked to human chromosome 20 | Gwilliam, Rhian | 2004 | Not available |
Computational Detection and Analysis of Polyadenylation Signals | Hajarnavis, Ashwin | 2005 | |
Phenotypic and Functional Characterisation of Innate and Adaptive Immune Responses after Mucosal Vaccination | Hall, Lindsay | 2007 | |
Prediction and analysis of nucleosome positioning in genomic sequences | Hasan, Samiul | 2003 | |
Genomic variation and evolution of Clostridium difficile | He, Miao | 2011 | |
DNA polymerase mutations as drivers of genome instability and cancer | Herzog, Mareike | 2016 | |
A functional genomic-based study of the streptomycin mouse model of human Salmonella Typhimurium gastroenteritis | Hill, Jennifer | 2015 | |
Progressive hearing loss in mouse mutants | Hilton, Jennifer | 2012 | Not available |
Studies in probabilistic sequence alignment and evolution | Holmes, Ian | 1998 | |
Genomic variation and evolution of Salmonella enterica serovars Typhi and Paratyphi A | Holt, Kathryn | 2009 | |
Identification of novel Plasmodium Vivax blood-stage vaccine targets | Hostetler, Jessica Blythe | 2016 | |
Gene prediction using a configurable system for the integration of data by Dynamic programming | Howe, Kevin | 2003 | |
Physical, transcriptional and comparative mapping on the human X chromosome | Howell, Gareth | 2002 | |
Positive natural selection in the human genome | Hu, Min | 2012 | |
Whole-genome Sequencing-based Association Studies of Cardiovascular Biomarkers | Huang, Jie | 2015 | |
The functional impact of copy number variation in the human genome | Huang, Ni | 2011 | |
Computational detection of non-coding RNAs in genomes | Huang, Yen-Hua | 2008 | |
Genome plasticity and genetic exchange in Leishmania tropica | Iantorno, Stefano | 2015 | |
Characterization of Cancer Gene Mutations in Human Cancer Cell lines for Correlation with Drug Activity | Ikediobi, Ogechi | 2008 | |
Identification of target genes of an erythroid transcription factor complex containing SCL(TAL1) | Jim, Hau Ling | 2008 | |
A role for microRNA-155 in the control of infection | John, Victoria | 2010 | |
Computational analysis of the Caenorhabditis elegans genome sequence | Jones, Steve | 1999 | Not available |
Genetic and phenotypic investigations into developmental disorders | Jones, Wendy Dawn | 2017 | |
Using Next-Generation Genomic Datasets In Disease Association | Jostins, Luke | 2012 | |
Molecular characterization and computational analysis of constitutional chromosome rearrangements | Kalaitzopoulos, Dimitrios | 2006 | Not available |
Identification of Genetic Differences Between Strains of Campylobacter jejuni | Kay, Emily | 2005 | |
Investigations into the Rab family of genes and their roles in signalling during vertebrate early development | Kenyon, Emma | 2006 | |
Uniparental disomy and mosaic structural variation in developmental disorders | King, Daniel Alexander | 2015 | |
Single cell mRNA-sequencing of mESCs reveals cell-to-cell variation in pluripotency and cell cycle genes | Kolodziejczyk, Aleksandra Anna | 2016 | |
Transposon-mediated Insertional Mutagenesis in Gene Discovery and Cancer | Kong, Jun | 2011 | |
Cas9-induced on-target genomic damage | Kosicki, Michal Konrad | 2018 | |
Genome-Wide Translational Control In Fission Yeast | Lackner, Daniel | 2007 | |
The ribosomal RNA processing gene nucleolar protein 9 (nol9) is essential for normal exocrine pancreas development in zebrafish | Lam Hung, Laure | 2013 | |
Karyotype Evolution: Evolutionary Chromosome Rearrangements in Material Homologous to Human Chromosome 22q Studied in the Dog and Gibbon | Langford, Cordelia | 2003 | |
Metabolic capability in host-restricted serovars of Salmonella enterica | Langridge, Gemma C | 2010 | |
Characterisation of bcl11 functions in development using genetically modified mice | Lee, Song Choon | 2008 | |
Host and pathogen genetics associated with pneumococcal meningitis | Lees, John Andrew | 2017 | |
Somatic evolution in human blood and colon | Lee-Six, Henry | 2018 | |
A genetic screen for tumour suppressor genes using the sleeping beauty and piggybac transposon systems | Liang, Qi | 2009 | Not available |
A recessive genetic screen to discover components in miRNA pathways using piggyBac-mediated insertional mutagenesis in Blm-deficient mouse embryonic stem cells | Li, Meng | 2010 | |
Genetic Dissection of the Exit from Pluripotency in Mouse Embryonic Stem Cells by CRISPR-based Screening | Li, Meng | 2017 | |
Reprogramming of T cells to natural killer-like cells upon BCL11B deletion | Li, Peng | 2010 | |
The genetic architecture of immune-mediated complex diseases | Liu, Jimmy | 2014 | |
Evolutionary Landscape of CpG Island Methylation in X Chromosome Inactivation | Liu, Mengning | 2008 | |
Identification and Functional Characterisation of a Genetic Subset of Non-Small Cell Lung Cancer | Mahoney, Claire | 2009 | |
Genomic diversity and speciation in East African cichlid fish | Malinsky, Milan | 2015 | |
The role of microRNAs in neurons - (Also known as Sergei A Manakov) | Manakou, Siarhei | 2011 | |
Analysis of genome-wide, cancer-associated mutation datasets in mouse and human | Mattison, Jenny | 2008 | |
Schizosaccharomyces pombe: from sequence to function | McDougall, Rachel C | 1997 | Not available |
Mathematical methods for comparative ab initio gene prediction | Meyer, Imtraud | 2002 | |
Modelling Human Genetic Disorders in Mice | Migdalska, Anna | 2011 | |
Analysis of genetic variation data using Ancestral Recombination Graphs | Minichiello, Mark | 2007 | |
Evolution and gene regulation of the genomic imprinting mechanism | Mungall, Andy | 2007 | |
The Origins and Evolution of Vibrio cholerae O1 El Tor | Mutreja, Ankur | 2014 | |
Analysis of the transcriptomes of wild-type and mutant C. elegans | Nelson, Andrew | 2008 | |
Regulatory variation and its role in disease | Nica, Alexandra C | 2010 | |
Exploring mutational signatures in twenty-one breast cancers | Nik-Zainal, Serena | 2012 | |
Genetic dissection of EGFRvIII brain and spinal mouse gliomas through whole-exome sequencing and in vivo piggyback mutagenesis forward genetic screening | Noorani, Imran | 2018 | |
The Role of Retinoic Acid Receptors in the Replacement of Oct4 during the Generation of Induced Pluripotent Stem Cells | Ooi, Jolene | 2012 | |
Genetic mapping of cellular traits | Parts, Leopold | 2011 | |
Maps of open chromatin - from genetic signals to function | Paul, Dirk | 2012 | |
Characterisation of the Transcriptome and Proteome of Salmonella enterica subspecies enterica serovar Typhi | Perkins, Timothy | 2009 | |
Identification and characterisation of host-pathogen protein-protein interactions in the blood stages of malaria | Perrin, Abigail | 2014 | |
Defining the Clostridium difficile spo0A regulon and its role in disease and transmission | Pettit, Laura J | 2012 | |
Isolation of homozygous mutant mouse embryonic stem cells by selection for copy number increase | Pettitt, Stephen J | 2011 | |
Analysis of IncHI1 plasmids in Salmonella enterica serovar Typhi | Phan, Minh-Duy | 2009 | |
Inference and classification of eukaryotic cis-regulatory motifs | Piipari, Matias | 2010 | |
Characterising antibiotic susceptibility and resistance in human commensal gut bacteria | Pike, Lindsay Jacqueline | 2019 | |
Tissue-specific adaptations of cell types | Pires de Carvalho Gomes, Tomás | 2020 | |
Computational Analysis of Genomes | Pocock, Matthew R | 2003 | |
The Zebrafish Homologues of JAM-B and JAM-C are Essential for Myoblast Fusion | Powell, Gareth T | 2010 | |
Transcriptome characterisation of cercariae and skin-stage schistosomula in the parasitic helminth Schistosoma mansoni. | Protasio, Anna V | 2011 | |
Computational detection of gene regulatory signals in human genome sequence | Ramadass, Aroul S | 2004 | |
Genome Evolution: A study of MHC paralogous genes in the human genome | Rand, Vikki | 2003 | |
Neural network-based methods for large scale protein sequence analysis. | Reinhardt, Astrid | 1999 | Not available |
Patterns of somatic genome rearrangement in human cancer | Roberts, Nicola Diane | 2018 | |
Murine embryonic stem cells as a route towards exploring host-pathogen interactions | Rossi, Raffaella | 2008 | |
Human Cellular Genetics of Innate Immunity | Rostom, Raghd | 2019 | Not available |
Periodic gene expression program of the fission yeast cell cycle | Rustici, Gabriella | 2004 | |
Functional investigation of NMDA receptor molecular evolution | Ryan, Tomas | 2010 | Not available |
The influence of genetics on gamma-herpesvirus infections | Sallah, Neneh | 2016 | |
Analysis of gene amplification in human cancer | Santarius, Tom | 2009 | Not available |
The role of protein interactions in evolution and disease | Schuster-Bockler, Benjamin | 2008 | |
Using molecular QTLs to identify cell types and causal variants for complex traits | Schwartzentruber, Jeremy | 2017 | |
The role of the CapZ complex in vertebrate sarcomere integrity | Scott, Annabelle | 2007 | |
Transcriptome characterisation of the intra-mammalian stage of male and female Schistosoma mansoni | Sessler, Andreas Florian | 2017 | |
Extracellular receptor-ligand interaction screening using CRISPR activation | Shan, Chong Zheng | 2018 | |
Genome-scale identification of cellular pathways required for cell surface recognition | Sharma, Sumana | 2017 | |
Efficient sequence assembly and variant calling using compressed data structures | Simpson, Jared | 2012 | |
The contribution of rare variants to risk of schizophrenia and neurodevelopmental disorders | Singh, Tarjinder | 2017 | |
Genome studies of human chromosome 22q13.3. | Smink, Luc | 2000 | Not available |
The Function and Genetics of the Host IFITM Locus | Smith, Sarah | 2014 | |
Genetic and environmental regulation of olfactory sensory neurone diversity | Soria, Ximena Ibarra | 2015 | |
Human chromosome 20q12-13.2: Structural, comparative and sequence variation studies | Stavrides, George | 2002 | |
Methods for genome-scale gene perturbation studies of the TRAIL-induced apoptosis pathway in mammalian cell culture | Sudbery, Ian | 2007 | |
Fine-mapping and functional analyses of genetic variants driving local adaptations in humans | Szpak, Michal | 2016 | |
Copy Number Variation and Schizophrenia | Tam, Gloria Wing Chi | 2008 | |
The targets and role of palmitoylation in Plasmodium parasites | Tay, Chwen Ling | 2014 | |
Molecular characterisation of the candidate region for bronx waltzer: a mouse model of hearing impairment | Taylor, Amy | 2005 | |
Analysis of genes controlling notochord development in zebrafish | Thomas, Kevin | 2005 | |
Characterization of a Novel Deletion Allele of Brca1 | Thompson, Debrah M | 2003 | |
Systematic Analysis of the Evolution and Conservation of Genetic Interactions Using C. elegans as a Model System | Tischler, Julia | 2007 | |
Identification and Characterisation of Differentially Methylated Regions within the human Major Histocompatibility Complex | Tomazou, Eleni M | 2008 | |
Application of CRISPR/Cas9 screening to study cancer drivers and to identify novel cancer vulnerabilities | Turner, Gemma | 2019 | |
In silico prediction of Genomic In Islands in microbial genomes Islands | Vernikos, George | 2008 | |
Biochemical investigations of Plasmodium falciparum erythrocyte invasion pathways using recombinant merozoite surface proteins produced in a mammalian expression system | Wanaguru, Madushi | 2012 | |
Characterization of BCL11 functions in the mouse mammary gland identifies two types of mammary stem cells | Wang, Juexuan | 2012 | Not available |
Chromosome-specific Recessive Genetic Screen for Genes Involved in In Vitro Differentiation in Mouse Embyonic Stem Cells | Wang, Wei | 2005 | |
Transcriptomic studies on host-parasite interactions in Schistosoma mansoni intramammalian stages | Wangwiwatsin, Arporn | 2017 | |
Analysis of short tandem repeat variation in large scale resequencing data | Whitener, Weldon | 2011 | |
Application of DNA Microarrays to Assess DNA Replication Timing and Chromosomal Aberrations | Woodfine, Kathryn | 2003 | |
Genome-wide recessive screens for DNA mismatch repair genes in mouse ES cells | Xiong, Zikai | 2008 | |
Biological Investigations through sequence analysis | Yeats, Corin | 2004 | |
Progressive hearing loss in mouse mutants | Yen, Jennifer | 2012 | Not available |
Evolution by Gene Loss? | Yngvadottir, Bryndis | 2008 | |
Identification and analysis of MHC-linked olfactory receptor genes | Younger, Ruth | 2002 | |
Applying recombinant protein technology to study Plasmodium falciparum erythrocyte receptor-ligand interactions and their potential as therapeutic targets | Zenonos, Zenon | 2013 | |
Mapping synaptic heterogeneity of MAGUK family members in fluorescent protein knockin mice | Zhu, Fei | 2012 | Not available |
MPhil Theses
Title | Author | Year | Thesis |
---|---|---|---|
Epidemiology and Genomic Diversity of Staphylococcus aureus in Humans and Pigs in Kenya | Bett, Vincent Kiplangat | 2018 | |
Genetic diversity and distribution of the pneumococcal surface lipoproteins and implications on potential proteinbased vaccines | Bojang, Ebrima | 2017 | |
Development of a Resource for the Exploration of Gene Expression in the Mouse Foetus | Campbell, Elizabeth A | 2004 | |
Characterisation of the transcriptional response to cytokine induced polarisation in human CD4+ T cells and monocyte derived macrophages | Cano Gámez, Eddie | 2017 | |
Identifying mediators of malignant transformation in human cancer using genome-wide forward genetic screening approaches | Dunstone, Eleanor | 2018 | |
The relationship of identity by state to identity by descent and imputation accuracy in population sequencing data | Harris, Kelley | 2011 | |
Phenotypic variation in erythrocyte invasion by Plasmodium falciparum isolates from Peru | Hesketh, Richard | 2011 | |
Overexpression of Mammalian Nanog mRNA Hyperdorsalises Zebrafish Embryos | Jiang, Ying | 2011 | |
Comparative genomics of Escherichia coli causing bloodstream infections in the Hospital for Tropical Diseases, Ho Chi Minh city, Vietnam | Le, Tu Thi Phuong | 2017 | |
Bioinformatics approaches to RNA splicing | Levine, Aaron | 2001 | |
Identification of Extrachromosomal Elements from Whole Genome Sequences of the Human Gut Microbiome to Investigate the Gut Mobilome and Resistome | Mkandawire, Tapoka Thulisile | 2017 | |
RNA sequencing analysis of Plasmodium falciparum extracellular vesicles | Mwikali, Kioko | 2018 | |
Somatic mutations in the pancreatic islets | Nicola, Pantelis Andreas | 2018 | |
Understanding neurodegenerative diseases in human iPS cell models by genome editing with CRISPR-Cas9 | Qarin, Shamma | 2016 | |
Bioinformatic Analysis of Imprinted CpG Islands in Mus musculus | Riordan, Daniel | 2003 | |
Machine Learning for Precision Oncology: Genomic Classification and Analysis of Diffuse Large B Cell Lymphoma | Ruiz, Camilo | 2017 | |
Evaluating the Efficacy of Epigenetic Imputation in CD4+ Regulatory T Cells | Thurimella, Kiran Kumar | 2018 | |
Integrating single-cell transcriptomics with orthogonal experimental approaches and datasets to enhance characterization of the maternal-fetal interface | Zou, Angela Elizabeth | 2018 |