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In our JCI Insight paper just out it was hard to separate developmental trajectories for allo-reactive Th1, Th17 and iTreg by #scRNAseq. Instead, we found quiescent Tcf7+ gut migratory CD4+ T cells that retained effector potential in #GvHD. Read for FREE! https://insight.jci.org/articles/view/137990
Are you into tissue clearing for #microscopy? The Nikon CFI90 20XC Glyc #objective provides an ultralong working distance of 8.2mm, NA = 1.0, and superior transmittance and aberration correction to 1300nm. Click to learn more. #neuroscience #multiphoton https://qoo.ly/36z7ym
Our study of aneuploidy in human preimplantation embryos is now published in @genomeresearch. We combined signatures of chromosome-wide gene expression and allelic imbalance to discover meiotic and mitotic-origin aneuploidy in single-cell RNA-seq data: http://www.genome.org/cgi/doi/10.1101/gr.262774.120