Dr Dirk Paul

Visiting Scientist

Dirk's research focuses on the translation of genomic discoveries in cardiovascular and immune-related diseases into biological and clinical insights. The aim of my research is to identify and characterise causal biological pathways in cardiovascular disease. We integrate computational analyses and cutting-edge experimental strategies to uncover the molecular, cellular and physiological mechanisms underlying genetic associations with cardiovascular disease.

I graduated with a BSc and MSc in Life Science from the University of Konstanz (Germany) in 2008. With the support of Marie Curie and Wellcome Trust Fellowships, I completed a PhD in Molecular Biology and Genetics under the supervision of Prof Panos Deloukas at the Wellcome Sanger Institute in 2012, where I combined experimental and computational approaches to uncover the molecular mechanisms of genetic variants associated with haematological traits. I did postdoctoral studies in epigenomics of immune-related diseases in Prof Stephan Beck’s laboratory at University College London as part of the BLUEPRINT Consortium. In 2015, I joined the Cardiovascular Epidemiology Unit at the University of Cambridge as University Lecturer in Integrative Genomics.

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New preprint!

We analyzed raw abdominal MRI imaging data from >36K individuals

“Machine learning enables new insights into clinical significance of and genetic contributions to liver fat accumulation”

Paper: https://bit.ly/2ZHzDEK
Medrxiv: https://bit.ly/32CG79X