Dr Daniele Muraro
This person is a member of Sanger Institute Alumni.
Daniele passed away in October 2022. This page is being maintained as a historical record of his work at the Sanger Institute.
My role involves: management and analysis of large scale multi-modal and spatial genomics data obtained in the Human Cell Atlas; development of new computational methods used within the Teichmann Group research programme.
I graduated with a PhD in Mathematical Physics (University of Milan) in the area of Dynamical Systems, I have since held four postdoctoral positions (Universities of Lisbon, Nottingham and Oxford) in Mathematical / Systems Biology during which I applied and developed a range of computational techniques to investigate different biological systems (Drosophila embryos, Arabidopsis thaliana roots, intestinal epithelium, hiPSCs, organoids). My computational work focused on the areas of modelling, prioritisation, reverse-engineering of molecular interaction networks, evolutionary computation, analysis of gene expression data (including Single Cell RNA-Seq), mathematical models to study cell proliferation, differentiation and death (pattern formation, mechanistic growth, cell population dynamics).
In May 2017 I joined the Wellcome Sanger Institute, where I have led the bioinformatics analysis in a variety of projects mostly based on (Single Cell) RNA-Seq data, CRISPR screens with single cell readouts and, more recently, large scale multi-modal and spatial genomics data.
Joined Wellcome Sanger Institute as Staff Scientist
Postdoctoral Researcher, Mathematical Institute, University of Oxford, UK.
Postdoctoral Researcher, The Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, UK.
Postdoctoral Researcher, Centre for Plant Integrative Biology (CPIB), School of Biosciences, University of Nottingham, UK.
Postdoctoral Researcher, Department of Physics, Technical University of Lisbon, Portugal.
Graduated with a PhD in Mathematics, Mathematical Physics, University of Milan, Italy.