Dr Arthur M Talman | Postdoctoral Fellow

This person is a member of Sanger Institute Alumni.

Talman, Arthur M

My current research focuses on understanding the strategies and patterns observed during malaria sexual reproduction. Male and female parasites are picked up during mosquito feeding, mate in the blood meal and are responsible for malaria transmission. The aim of my research is to understand how distinct parasite populations interact during this process.

Throughout my studies I have been interested in host-pathogen interactions and mechanisms of malaria transmission. In particular, I participated in field studies of apicomplexan parasite transmission in rural Africa and Southeast Asia. For my PhD at Imperial College London, I investigated malaria sexual reproduction and transmission to Anopheline mosquitoes from a molecular perspective. I recently completed my post-doctoral training by conducting research into dissemination of bacterial and viral pathogens at the Yale School of Medicine’s Microbial Pathogenesis department. I joined Mara Lawniczak group in February 2015.


  • Bacterial spread from cell to cell: beyond actin-based motility.

    Kuehl CJ, Dragoi AM, Talman A and Agaisse H

    Trends in microbiology 2015;23;9;558-66

  • An essential role of the basal body protein SAS-6 in Plasmodium male gamete development and malaria transmission.

    Marques SR, Ramakrishnan C, Carzaniga R, Blagborough AM, Delves MJ et al.

    Cellular microbiology 2015;17;2;191-206

  • Proteomic analysis of the Plasmodium male gamete reveals the key role for glycolysis in flagellar motility.

    Talman AM, Prieto JH, Marques S, Ubaida-Mohien C, Lawniczak M et al.

    Malaria journal 2014;13;315

  • Actin network disassembly powers dissemination of Listeria monocytogenes.

    Talman AM, Chong R, Chia J, Svitkina T and Agaisse H

    Journal of cell science 2014;127;Pt 1;240-9

  • PbGEST mediates malaria transmission to both mosquito and vertebrate host.

    Talman AM, Lacroix C, Marques SR, Blagborough AM, Carzaniga R et al.

    Molecular microbiology 2011;82;2;462-74

  • The Armadillo repeat protein PF16 is essential for flagellar structure and function in Plasmodium male gametes.

    Straschil U, Talman AM, Ferguson DJ, Bunting KA, Xu Z et al.

    PloS one 2010;5;9;e12901

  • Heritability of the human infectious reservoir of malaria parasites.

    Lawaly YR, Sakuntabhai A, Marrama L, Konate L, Phimpraphi W et al.

    PloS one 2010;5;6;e11358

  • A Plasmodium falciparum strain expressing GFP throughout the parasite's life-cycle.

    Talman AM, Blagborough AM and Sinden RE

    PloS one 2010;5;2;e9156

  • Attraction between sexes: male-female gametocyte behaviour within a Leucocytozoon toddi (Haemosporida).

    Barraclough RK, Duval L, Talman AM, Ariey F and Robert V

    Parasitology research 2008;102;6;1321-7

  • Influence of chemotherapy on the Plasmodium gametocyte sex ratio of mice and humans.

    Talman AM, Paul RE, Sokhna CS, Domarle O, Ariey F et al.

    The American journal of tropical medicine and hygiene 2004;71;6;739-44

Talman, Arthur M
Arthur's Timeline

Postdoctoral Fellow, WTSI


Postdoctoral Fellow and Assistant in Instruction, Yale School of Medicine


PhD, Imperial College London


Research Assistant, Institut Pasteur du Cambodge


Research Assistant, Institut Pasteur de Madagascar