Nicola D Roberts | Former PhD Student at the Sanger Institute

This person is a member of Sanger Institute Alumni.

Roberts, Nicola D

My PhD project focuses on the analysis and interpretation of structural variation in ~2500 cancer genomes sequenced by the International Cancer Genome Consortium. My research interests include statistical method development for cancer genomics data, and the causes and consequences of somatic (acquired) mutation.


  • Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing.

    Cortés-Ciriano I, Lee JJ, Xi R, Jain D, Jung YL et al.

    Nature genetics 2020

  • Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer.

    Akdemir KC, Le VT, Chandran S, Li Y, Verhaak RG et al.

    Nature genetics 2020

  • Genomic footprints of activated telomere maintenance mechanisms in cancer.

    Sieverling L, Hong C, Koser SD, Ginsbach P, Kleinheinz K et al.

    Nature communications 2020;11;1;733

  • Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition.

    Rodriguez-Martin B, Alvarez EG, Baez-Ortega A, Zamora J, Supek F et al.

    Nature genetics 2020

  • Pan-cancer analysis of whole genomes.

    ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium

    Nature 2020;578;7793;82-93

  • Patterns of somatic structural variation in human cancer genomes.

    Li Y, Roberts ND, Wala JA, Shapira O, Schumacher SE et al.

    Nature 2020;578;7793;112-121

Roberts, Nicola D