Nicola D Roberts | Former PhD Student at the Sanger Institute

This person is a member of Sanger Institute Alumni.

Roberts, Nicola D

My PhD project focuses on the analysis and interpretation of structural variation in ~2500 cancer genomes sequenced by the International Cancer Genome Consortium. My research interests include statistical method development for cancer genomics data, and the causes and consequences of somatic (acquired) mutation.

Publications

  • Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing.

    Cortés-Ciriano I, Lee JJ, Xi R, Jain D, Jung YL et al.

    Nature genetics 2020

  • Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer.

    Akdemir KC, Le VT, Chandran S, Li Y, Verhaak RG et al.

    Nature genetics 2020

  • Genomic footprints of activated telomere maintenance mechanisms in cancer.

    Sieverling L, Hong C, Koser SD, Ginsbach P, Kleinheinz K et al.

    Nature communications 2020;11;1;733

  • Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition.

    Rodriguez-Martin B, Alvarez EG, Baez-Ortega A, Zamora J, Supek F et al.

    Nature genetics 2020

  • Pan-cancer analysis of whole genomes.

    ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium

    Nature 2020;578;7793;82-93

  • Patterns of somatic structural variation in human cancer genomes.

    Li Y, Roberts ND, Wala JA, Shapira O, Schumacher SE et al.

    Nature 2020;578;7793;112-121

Roberts, Nicola D