Dr Maria Nascimento Primo | Postdoctoral Fellow

Primo, Maria Nascimento

After completing my PhD work in the Department of Biomedicine, Aarhus University, I've joined the Gaffney's group as a postdoctoral fellow. My main focus is to gain deeper understanding of the fundamental gene regulatory processes and the downstream signalling pathways regulating proinflammatory and tolerogenic profiles in human macrophages and dendritic cells. Because diversity and plasticity are outstanding hallmarks of immune cells, I'm exploring single-cell RNA-sequencing techniques to monitor cellular heterogeneity and population dynamics after cell stimulation. 

Publications

  • MicroRNA-155 controls vincristine sensitivity and predicts superior clinical outcome in diffuse large B-cell lymphoma.

    Due H, Schönherz AA, Ryø L, Primo MN, Jespersen DS et al.

    Blood advances 2019;3;7;1185-1196

  • Psoriasiform skin disease in transgenic pigs with high-copy ectopic expression of human integrins α2 and β1.

    Staunstrup NH, Stenderup K, Mortensen S, Primo MN, Rosada C et al.

    Disease models & mechanisms 2017;10;7;869-880

  • High miR-34a expression improves response to doxorubicin in diffuse large B-cell lymphoma.

    Marques SC, Ranjbar B, Laursen MB, Falgreen S, Bilgrau AE et al.

    Experimental hematology 2016;44;4;238-46.e2

  • Anti-Apoptotic Effects of Lentiviral Vector Transduction Promote Increased Rituximab Tolerance in Cancerous B-Cells.

    Ranjbar B, Krogh LB, Laursen MB, Primo MN, Marques SC et al.

    PloS one 2016;11;4;e0153069

  • Potent microRNA suppression by RNA Pol II-transcribed 'Tough Decoy' inhibitors.

    Bak RO, Hollensen AK, Primo MN, Sørensen CD and Mikkelsen JG

    RNA (New York, N.Y.) 2013;19;2;280-93

  • Regulation of pro-inflammatory cytokines TNFα and IL24 by microRNA-203 in primary keratinocytes.

    Primo MN, Bak RO, Schibler B and Mikkelsen JG

    Cytokine 2012;60;3;741-8

  • Lentiviral vectors for cutaneous RNA managing.

    Primo MN, Bak RO and Mikkelsen JG

    Experimental dermatology 2012;21;3;162-70

  • Development of transgenic cloned pig models of skin inflammation by DNA transposon-directed ectopic expression of human β1 and α2 integrin.

    Staunstrup NH, Madsen J, Primo MN, Li J, Liu Y et al.

    PloS one 2012;7;5;e36658

Primo, Maria Nascimento
Maria's Timeline
2017

Postdoc at the Wellcome Trust Sanger Institute

PhD in Medicine, Depart of Biomedicine, Aarhus University

Joined the Wellcome Trust Sanger Institute

2012

Joined the Aarhus Research Center for Innate Immunology

2011

MSc in Molecular Biology and Genetics, Faculty of Science, Lisbon University

2009

BSc in Biotechnology and Cellular Biology, Faculty of Science, Lisbon University