I am a Wellcome Trust Intermediate Clinical Fellow based at Sanger and the University Department of Paediatrics (Cambridge). My research aims to utilise sequencing technologies to understand the basis of childhood cancers within the context of normal cells and human development. My research is funded by the Wellcome Trust and the St. Baldrick's Foundation.
Retracing embryological fate.
Science (New York, N.Y.) 2016;354;6316;1109
Mutational signatures of ionizing radiation in second malignancies.
Nature communications 2016;7;12605
Genome sequencing of normal cells reveals developmental lineages and mutational processes.
Recurrent PTPRB and PLCG1 mutations in angiosarcoma.
Nature genetics 2014;46;4;376-379
Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone.
Nature genetics 2013;45;12;1479-82
Frequent mutation of the major cartilage collagen gene COL2A1 in chondrosarcoma.
Nature genetics 2013;45;8;923-6