Cytometry Core Facility

Cellular Operations

The flow cytometry facility at the Wellcome Sanger Institute is a dedicated scientific service offering researchers with state-of-the-art flow cytometry instrumentation. Additionally, we offer flow cytometer training alongside assistance with running samples, data analysis and experimental design. The facility supports a range of flow cytometry techniques and currently has 9 instruments, including 2 with cutting edge spectral detection technology. High performance cell sorting is also provided as an application. Our sorters are customized for isolating cells and chromosomes at high speed.

Flow Cytometry is a laser based technology that is used to measure the physical and chemical characteristics of cells. Such measurements are made while the cells flow in a liquid medium past an excitation light source and the emitted fluorescence captured by its measuring apparatus. It is an important tool for many scientific disciplines as it allows qualitative and quantitative examination of the whole cells as well as characterization of cells within a sample.

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Our people

Group lead

Bee Ling Ng

Senior Scientific Manager

The Cytometry Core Facility team is made up of staff members all with many years of experience in different aspects of flow cytometry. We dedicate our time and efforts in helping and assisting our researchers in their flow cytometry experiments. The facility collaborates with various research projects using flow cytometric techniques to isolate and purify cells and chromosomes for structural and functional studies, CRISPR screening, further downstream processing using 10X genomics and sequencing.